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X 射线能谱和蝴蝶结滤线器特性对蒙特卡罗模拟器官剂量准确性的影响:在全身 CT 扫描模式下的验证。

Influence of X-ray spectrum and bowtie filter characterisation on the accuracy of Monte Carlo simulated organ doses: Validation in a whole-body CT scanning mode.

机构信息

Department of Human Structure and Repair, Ghent University, Proeftuinstraat 86 - Building N7, 9000 Ghent, Belgium.

Department of Nuclear Medicine, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium; Department of Diagnostic Sciences, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

出版信息

Phys Med. 2024 Nov;127:104837. doi: 10.1016/j.ejmp.2024.104837. Epub 2024 Oct 25.

Abstract

PURPOSE

For patient-specific CT dosimetry, Monte Carlo dose simulations require an accurate description of the CT scanner. However, quantitative spectral information and information on the bowtie filter material and shape from the manufacturer is often not available. In this study, the influence of different X-ray spectra and bowtie filter characterisation methods on simulated CT organ doses is studied.

METHODS

Using ImpactMC, organ doses of whole-body CTs were simulated in twenty adult whole-body voxel models, generated from PET/CT examinations previously conducted in these patients. Simulated CT organ doses based on the manufacturer X-ray spectra and bowtie filter data were compared with those obtained using alternative characterisation models, including spectrum generators and experimentally measured dose data. A total of four different X-ray spectra and one bowtie filter model were defined based on these data.

RESULTS

For all X-ray spectra and bowtie filter combinations, estimated CT organ doses are within 6% from those resulting from simulations with the CT characterisation models provided by the manufacturer. While varying the bowtie filter model results in CT organ dose differences smaller than 1%, dose differences up to 6% are observed when X-ray spectra are not based on the quantitative data from the manufacturer.

CONCLUSIONS

Estimated organ doses slightly depend on the applied CT characterisation model. When manufacturer's data are not available, half-value layer and dose measurements provide sufficient input to obtain equivalent X-ray spectra and bowtie filter profiles, respectively.

摘要

目的

对于特定于患者的 CT 剂量学,蒙特卡罗剂量模拟需要对 CT 扫描仪进行准确描述。然而,制造商通常无法提供定量光谱信息以及关于弓带状滤线器材料和形状的信息。在这项研究中,研究了不同 X 射线光谱和弓带状滤线器描述方法对模拟 CT 器官剂量的影响。

方法

使用 ImpactMC,基于先前在这些患者中进行的 PET/CT 检查生成的二十个成人全身体素模型,模拟全身 CT 的器官剂量。基于制造商的 X 射线光谱和弓带状滤线器数据模拟的 CT 器官剂量与使用替代描述模型(包括光谱发生器和实验测量的剂量数据)获得的 CT 器官剂量进行了比较。总共基于这些数据定义了四个不同的 X 射线光谱和一个弓带状滤线器模型。

结果

对于所有 X 射线光谱和弓带状滤线器组合,估计的 CT 器官剂量与使用制造商提供的 CT 描述模型进行模拟的结果相差在 6%以内。虽然改变弓带状滤线器模型导致 CT 器官剂量差异小于 1%,但当 X 射线光谱不是基于制造商的定量数据时,观察到剂量差异高达 6%。

结论

估计的器官剂量略微取决于所应用的 CT 描述模型。当制造商的数据不可用时,半值层和剂量测量分别提供了足够的输入,以获得等效的 X 射线光谱和弓带状滤线器轮廓。

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