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一种基于蒙特卡罗方法的多探测器CT(MDCT)辐射剂量估算方法:圆柱形和体模。

A Monte Carlo based method to estimate radiation dose from multidetector CT (MDCT): cylindrical and anthropomorphic phantoms.

作者信息

DeMarco J J, Cagnon C H, Cody D D, Stevens D M, McCollough C H, O'Daniel J, McNitt-Gray M F

机构信息

David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

出版信息

Phys Med Biol. 2005 Sep 7;50(17):3989-4004. doi: 10.1088/0031-9155/50/17/005. Epub 2005 Aug 11.

Abstract

The purpose of this work was to extend the verification of Monte Carlo based methods for estimating radiation dose in computed tomography (CT) exams beyond a single CT scanner to a multidetector CT (MDCT) scanner, and from cylindrical CTDI phantom measurements to both cylindrical and physical anthropomorphic phantoms. Both cylindrical and physical anthropomorphic phantoms were scanned on an MDCT under the specified conditions. A pencil ionization chamber was used to record exposure for the cylindrical phantom, while MOSFET (metal oxide semiconductor field effect transistor) detectors were used to record exposure at the surface of the anthropomorphic phantom. Reference measurements were made in air at isocentre using the pencil ionization chamber under the specified conditions. Detailed Monte Carlo models were developed for the MDCT scanner to describe the x-ray source (spectra, bowtie filter, etc) and geometry factors (distance from focal spot to isocentre, source movement due to axial or helical scanning, etc). Models for the cylindrical (CTDI) phantoms were available from the previous work. For the anthropomorphic phantom, CT image data were used to create a detailed voxelized model of the phantom's geometry. Anthropomorphic phantom material compositions were provided by the manufacturer. A simulation of the physical scan was performed using the mathematical models of the scanner, phantom and specified scan parameters. Tallies were recorded at specific voxel locations corresponding to the MOSFET physical measurements. Simulations of air scans were performed to obtain normalization factors to convert results to absolute dose values. For the CTDI body (32 cm) phantom, measurements and simulation results agreed to within 3.5% across all conditions. For the anthropomorphic phantom, measured surface dose values from a contiguous axial scan showed significant variation and ranged from 8 mGy/100 mAs to 16 mGy/100 mAs. Results from helical scans of overlapping pitch (0.9375) and extended pitch (1.375) were also obtained. Comparisons between the MOSFET measurements and the absolute dose value derived from the Monte Carlo simulations demonstrate agreement in terms of absolute dose values as well as the spatially varying characteristics. This work demonstrates the ability to extend models from a single detector scanner using cylindrical phantoms to an MDCT scanner using both cylindrical and anthropomorphic phantoms. Future work will be extended to voxelized patient models of different sizes and to other MDCT scanners.

摘要

这项工作的目的是将基于蒙特卡洛方法估算计算机断层扫描(CT)检查中辐射剂量的验证范围,从单一CT扫描仪扩展到多探测器CT(MDCT)扫描仪,并从圆柱形头部剂量模体测量扩展到圆柱形和物理人体模体测量。在指定条件下,在MDCT上对圆柱形和物理人体模体进行扫描。使用铅笔电离室记录圆柱形模体的照射量,而使用金属氧化物半导体场效应晶体管(MOSFET)探测器记录人体模体表面的照射量。在指定条件下,使用铅笔电离室在等中心的空气中进行参考测量。为MDCT扫描仪开发了详细的蒙特卡洛模型,以描述X射线源(光谱、蝴蝶结滤波器等)和几何因素(从焦点到等中心的距离、轴向或螺旋扫描引起的源移动等)。圆柱形(头部剂量模体)模体的模型可从先前的工作中获得。对于人体模体,使用CT图像数据创建模体几何形状的详细体素化模型。人体模体的材料成分由制造商提供。使用扫描仪、模体和指定扫描参数的数学模型对物理扫描进行模拟。在与MOSFET物理测量对应的特定体素位置记录计数。进行空气扫描模拟以获得归一化因子,将结果转换为绝对剂量值。对于头部剂量模体(32 cm),在所有条件下测量结果与模拟结果的误差在3.5%以内。对于人体模体,连续轴向扫描测得的表面剂量值显示出显著变化,范围为8 mGy/100 mAs至16 mGy/100 mAs。还获得了重叠螺距(0.9375)和扩展螺距(1.375)的螺旋扫描结果。MOSFET测量结果与蒙特卡洛模拟得出的绝对剂量值之间的比较表明,在绝对剂量值以及空间变化特征方面具有一致性。这项工作证明了将模型从使用圆柱形模体的单探测器扫描仪扩展到使用圆柱形和人体模体的MDCT扫描仪的能力。未来的工作将扩展到不同尺寸的体素化患者模型以及其他MDCT扫描仪。

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