Garabedian-Ruffalo S M, Ruffalo R L
Am Fam Physician. 1986 Feb;33(2):165-74.
The pharmacokinetic and pharmacodynamic parameters of many commonly used drugs can be affected by diet. Conversely, nutritional status can be altered by various medications. These interactions become clinically significant when they alter the intended response to a drug or impair the patient's nutritional status.
许多常用药物的药代动力学和药效学参数会受到饮食的影响。反之,营养状况也会因各种药物而改变。当这些相互作用改变药物的预期反应或损害患者的营养状况时,就会在临床上产生显著影响。