Singh Karan Bir, Nguyen Katherine, Sammel Anthony, Wegner Eva A, Ho Shon Ivan
Department of Nuclear Medicine and PET, The Prince of Wales Hospital, Sydney, New South Wales, Australia.
Department of Rheumatology, The Prince of Wales Hospital, Sydney, 2031, New South Wales, Australia.
J Med Imaging Radiat Oncol. 2024 Dec;68(8):881-892. doi: 10.1111/1754-9485.13800. Epub 2024 Oct 27.
Large vessel vasculitides (LVV) such as giant cell arteritis, Takayasu arteritis and aortitis/periaortitis are characterised by immune-mediated inflammation of medium to large arteries. Clinical disease manifestations can be non-specific and diagnostic imaging plays an important role in the diagnostic pathway. In recent years, FDG PET/CT has proven to be a powerful metabolic tool that can provide a wholed body, non-invasive assessment of vascular inflammation. This review outlines the clinical features of large vessel vasculitis and the closely related entity of polymyalgia rheumatica, summarises the evidence for FDG PET/CT in the assessment of these conditions, and provides guidance for patient preparation, image acquisition and interpretation.
大血管血管炎（LVV），如巨细胞动脉炎、高安动脉炎和主动脉炎/主动脉周炎，其特征是中到大动脉的免疫介导性炎症。临床疾病表现可能不具有特异性，诊断性影像学在诊断过程中起着重要作用。近年来，氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET/CT）已被证明是一种强大的代谢工具，可对血管炎症进行全身、非侵入性评估。本综述概述了大血管血管炎及与之密切相关的风湿性多肌痛的临床特征，总结了FDG PET/CT在评估这些疾病方面的证据，并为患者准备、图像采集和解读提供指导。
