Department of Anesthesiology, UZ Leuven, Department of Cardiovascular Sciences, Group Biomedical Sciences, Leuven, Belgium.
Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, Leuven, Belgium.
J Vet Med Sci. 2024 Dec 1;86(12):1299-1302. doi: 10.1292/jvms.24-0354. Epub 2024 Oct 25.
The aim of this pragmatic approach to retrospective observational study was to identify the end-tidal concentration of sevoflurane which was associated with optimal surgical conditions (i.e., absence of any movement, coughing and straining) in 127 pregnant sheep. Optimal surgical conditions were observed in 90% of the ewes with an end-tidal concentration of sevoflurane of 2.4 Vol-% [95% CI: 2.2; 2.8] during minimal-mild nociceptive stimuli (placement of arterial catheter, bladder catheter, shaving), with 4.4 Vol-% [95% CI: 4.0; 5.2] during maternal laparotomy and hysterotomy and with 4.4 Vol-% [95% CI: 3.9; 5.8] during subsequent manipulation of the uterus and fetal surgery.
本回顾性观察研究采用实用方法，旨在确定 127 只妊娠绵羊的呼气末七氟醚浓度，使其与最佳手术条件（即无任何运动、咳嗽和紧张）相关。在最小轻度伤害性刺激（放置动脉导管、膀胱导管、剃毛）时，呼气末七氟醚浓度为 2.4 体积%[95%CI：2.2；2.8]时，90%的母羊观察到最佳手术条件，在母体剖腹术和子宫切开术时为 4.4 体积%[95%CI：4.0；5.2]，在随后的子宫和胎儿手术操作时为 4.4 体积%[95%CI：3.9；5.8]。
