National Engineering Research Center of Foundational Technologies for CGT Industry, Shenzhen, People's Republic of China.
Shenzhen Kenuo Medical Laboratory, Shenzhen, People's Republic of China.
Cell Transplant. 2024 Jan-Dec;33:9636897241293628. doi: 10.1177/09636897241293628.
Cell counting is a common and fundamental cell measurement technique that plays a crucial role in the development and quality control of cell therapy products. However, accurate and reliable cell counting can be challenging owing to the complexity of cell preparations, diverse counting purposes, and various counting methods. This review summarizes the challenges encountered in cell counting for cell therapy products and provides strategies to improve the cell counting accuracy, thereby guiding the counting process and ensuring the quality of cell therapy products.
细胞计数是一种常见且基本的细胞测量技术，在细胞治疗产品的开发和质量控制中起着至关重要的作用。然而，由于细胞制剂的复杂性、不同的计数目的和各种计数方法，准确可靠的细胞计数具有一定的挑战性。本综述总结了细胞治疗产品细胞计数中遇到的挑战，并提供了提高细胞计数准确性的策略，从而指导计数过程，确保细胞治疗产品的质量。
