Raja Kalaiarasi, Thangavel Saranya, Kushwaha Akshat, Srinivas Bheemanathi Hanuman, Kar Rakhee, Alexander Arun, Penubarthi Lokesh Kumar, Saxena Sunil Kumar
Department of Otorhinolaryngology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Pondicherry, India.
Department of Otorhinolaryngology, Pondicherry Institute of Medical Sciences, Pondicherry, India.
Turk Arch Otorhinolaryngol. 2024 Oct 23;62(2):66-71. doi: 10.4274/tao.2023.2022-9-5.
This study aims to present a series of patients with disseminated rhinosporidosis with diagnostic and therapeutic features.
A retrospective study was conducted in a tertiary health care centre in South India from 2007 to 2020 with disseminated rhinosporidiosis. Twelve patients with multiple sites of involvement like the nose, nasopharynx, oropharynx, larynx, lacrimal sac and skin were included in the study. All patients underwent surgical excision, followed by peroral dapsone for one year.
The age group was around 30-55 years, with male predominance (11:1). Pond bathing history was present in 50% (n=6). The most common site of lesion was the nose (100%), oropharynx (83.3%), skin (75%), larynx (50%) and less commonly, nasopharynx (41.6%) and lacrimal sac (25%). One patient underwent surgery four times (8.3%), followed by thrice and twice by five (41.6%) and six (50%) patients, respectively. On two years of follow-up, two patients (16.6%) had a recurrence in the nose and larynx whereas eight patients (66.6%) had no recurrence and two patients (16.6%) were lost to follow-up.
This original article highlights the rare occurrence of disseminated rhinosporidiosis, the possibility of which should be kept in mind, mainly when two or more sites are involved. The most significant number of disseminated rhinosporidiosis cases in the literature is reported here. Dissemination with the cutaneous and multisite disease is rarely reported and poses difficulty in management. Early diagnosis and intervention prevent the dissemination of spores into various parts of the body.
本研究旨在介绍一系列播散性鼻孢子虫病患者的诊断和治疗特征。
于2007年至2020年在印度南部的一家三级医疗保健中心对播散性鼻孢子虫病进行了一项回顾性研究。该研究纳入了12例有多个受累部位(如鼻子、鼻咽、口咽、喉、泪囊和皮肤)的患者。所有患者均接受了手术切除,随后口服氨苯砜一年。
年龄组在30 - 55岁左右,男性居多(11:1)。50%(n = 6)的患者有池塘沐浴史。最常见的病变部位是鼻子(100%)、口咽(83.3%)、皮肤(75%)、喉(50%),较少见的是鼻咽(41.6%)和泪囊(25%)。1例患者接受了4次手术(8.3%),分别有5例(41.6%)和6例(50%)患者接受了3次和2次手术。在两年的随访中,2例患者(16.6%)在鼻子和喉部复发,而8例患者(66.6%)无复发,2例患者(16.6%)失访。
这篇原创文章强调了播散性鼻孢子虫病的罕见性,应牢记其发生的可能性,主要是在两个或更多部位受累时。本文报道了文献中数量最多的播散性鼻孢子虫病病例。皮肤和多部位疾病的播散很少被报道,且在管理上存在困难。早期诊断和干预可防止孢子播散到身体的各个部位。