Jiang QiHua, Hu Hai, Liao Jing, Duan Peng, Li ZhiHua, Tan JunTao
Department of Breast Surgery, Third Hospital of Nanchang, Nanchang City, Jiangxi Province, China.
Department of General Surgery, Third Hospital of Nanchang, Nanchang City, Jiangxi Province, China.
J Surg Oncol. 2025 Mar;131(4):587-597. doi: 10.1002/jso.27969. Epub 2024 Oct 28.
This study aims to evaluate the association between body mass index (BMI) and the incidence of breast cancer-related lymphedema (BCRL).
This retrospective cohort study analyzed data from 1464 breast cancer patients treated at The Third Hospital of Nanchang between 2018 and 2021. Patients were categorized based on BMI (<25, 25 to < 30, ≥ 30 kg/m²). Variables such as axillary lymph node dissection, infections, radiotherapy, and comorbidities were taken into account.
The incidence of BCRL was 23.4%. Higher BMI was associated with increased risk of BCRL, with significant incidence rates observed at 1, 2, and 3 years in the higher BMI groups. Multivariate analysis confirmed BMI as an independent risk factor for BCRL.
Elevated BMI is associated with increased BCRL risk and decreased BCRL-free survival, underscoring the significance of weight management in breast cancer care.
本研究旨在评估体重指数（BMI）与乳腺癌相关淋巴水肿（BCRL）发病率之间的关联。
这项回顾性队列研究分析了2018年至2021年期间在南昌大学第三附属医院接受治疗的1464例乳腺癌患者的数据。患者根据BMI进行分类（<25、25至<30、≥30kg/m²）。考虑了腋窝淋巴结清扫、感染、放疗和合并症等变量。
BCRL的发病率为23.4%。较高的BMI与BCRL风险增加相关，在较高BMI组中，1年、2年和3年时观察到显著的发病率。多变量分析证实BMI是BCRL的独立危险因素。
BMI升高与BCRL风险增加和无BCRL生存期缩短相关，强调了体重管理在乳腺癌护理中的重要性。
