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奇神经节阻滞术治疗外阴癌难治性慢性疼痛:一例报告

Ganglion Impar Neurolysis to Treat Refractory Chronic Pain From Vulvar Cancer: A Case Report.

作者信息

Akinwamide Oluwanifesimi, Syed Asad, Mehta Juhi, Andrawis Marina, Zhang Haijun

机构信息

Anesthesiology, Rutgers University New Jersey Medical School, Newark, USA.

出版信息

Cureus. 2024 Sep 24;16(9):e70128. doi: 10.7759/cureus.70128. eCollection 2024 Sep.

DOI:10.7759/cureus.70128
PMID:39463516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11502220/
Abstract

Cancer pain treatment currently consists of the administration of pain medications, radiation therapy, tumor ablation as well as neurolytic plexus blocks. Neurolytic plexus blocks target both sensory afferent fibers and sympathetic fibers innervating visceral organs. Finding the right block for a specific type and location of cancer-related pain is crucial for the successful control of pain. One such example is a ganglion impar block for perineal pain. We report a case of a patient with chronic severe perineal pain from vulvar cancer and multiple surgeries, for whom a ganglion impar block followed by neurolysis provided significant pain relief.

摘要

目前癌症疼痛治疗包括使用止痛药物、放射治疗、肿瘤消融以及神经溶解丛阻滞。神经溶解丛阻滞针对支配内脏器官的感觉传入纤维和交感神经纤维。为特定类型和部位的癌症相关疼痛找到合适的阻滞方法对于成功控制疼痛至关重要。一个这样的例子是阴部神经阻滞治疗会阴部疼痛。我们报告了一例患有外阴癌并接受多次手术导致慢性严重会阴部疼痛的患者,对其进行阴部神经阻滞后再行神经松解术,疼痛得到了显著缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2027/11502220/c530e5798e7b/cureus-0016-00000070128-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2027/11502220/c530e5798e7b/cureus-0016-00000070128-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2027/11502220/c530e5798e7b/cureus-0016-00000070128-i01.jpg

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Ganglion Impar Neurolysis to Treat Refractory Chronic Pain From Vulvar Cancer: A Case Report.奇神经节阻滞术治疗外阴癌难治性慢性疼痛:一例报告
Cureus. 2024 Sep 24;16(9):e70128. doi: 10.7759/cureus.70128. eCollection 2024 Sep.
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本文引用的文献

1
Cancer Pain Management-New Therapies.癌症疼痛管理——新疗法
Curr Oncol Rep. 2022 Feb;24(2):223-226. doi: 10.1007/s11912-021-01166-z. Epub 2022 Jan 26.
2
Efficacy of ganglion impar block on vulvodynia: Case series and results of mid- and long-term follow-up.阴部神经节阻滞治疗外阴痛的疗效:病例系列及中、长期随访结果。
Medicine (Baltimore). 2021 Jul 30;100(30):e26799. doi: 10.1097/MD.0000000000026799.
3
Comparative evaluation of transsacrococcygeal and transcoccygeal approach of ganglion impar block for management of coccygodynia.
经骶尾和经尾骨神经节阻滞治疗尾骨痛的比较评估
J Anaesthesiol Clin Pharmacol. 2021 Jan-Mar;37(1):90-96. doi: 10.4103/joacp.JOACP_588_20. Epub 2021 Apr 10.
4
Ganglion Impar Neurolysis in the Management of Pelvic and Perineal Cancer-Related Pain.奇神经节阻滞术在盆腔和会阴癌相关疼痛管理中的应用
Case Rep Oncol. 2020 Jan 20;13(1):29-34. doi: 10.1159/000505181. eCollection 2020 Jan-Apr.
5
Transcoccygeal neurolytic ganglion impar block for perineal pain: A case series.经尾骨神经节毁损性阻滞治疗会阴部疼痛:病例系列研究
J Anaesthesiol Clin Pharmacol. 2018 Oct-Dec;34(4):544-547. doi: 10.4103/joacp.JOACP_301_16.
6
Review of Sympathetic Blocks: Anatomy, Sonoanatomy, Evidence, and Techniques.交感神经阻滞:解剖学、超声解剖学、证据和技术综述。
Reg Anesth Pain Med. 2017 May/Jun;42(3):377-391. doi: 10.1097/AAP.0000000000000591.
7
Chemical neurolysis of the inferior hypogastric plexus for the treatment of cancer-related pelvic and perineal pain.下腹部盆腔丛化学松解术治疗癌症相关盆腔和会阴疼痛。
Pain Res Manag. 2013 Sep-Oct;18(5):249-52. doi: 10.1155/2013/196561. Epub 2013 May 28.
8
Ganglion impar blockade: a review.坐骨神经结阻滞:综述。
Curr Pain Headache Rep. 2013 Jan;17(1):306. doi: 10.1007/s11916-012-0306-7.
9
Transsacrococcygeal approach to ganglion impar for pelvic cancer pain: a report of 3 cases.经骶尾入路治疗盆腔癌性疼痛的奇神经节阻滞:3例报告
Reg Anesth Pain Med. 2008 Jul-Aug;33(4):381-2. doi: 10.1016/j.rapm.2008.01.006.
10
Transsacrococcygeal approach to ganglion impar block for management of chronic perineal pain: a prospective observational study.经骶尾骨入路奇神经节阻滞治疗慢性会阴痛:一项前瞻性观察研究
Pain Physician. 2007 Sep;10(5):661-6.