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血液透析患者动静脉分流的初级通畅成功率:一项为期28个月的前瞻性研究。

Primary Patency Success of Arteriovenous Shunts in Hemodialysis Patients: A 28-Month Prospective Study.

作者信息

Al Madhwahi Nabil, Al-Dailami Zaid, Al-Mashramah Gehad, Jowah Haitham M

机构信息

Department of Vascular Surgery, Faculty of Medicine and Health Science, Sana'a University, Sana'a, YEM.

Department of Vascular Surgery, Al-Thawra Modern General Hospital, Sana'a, YEM.

出版信息

Cureus. 2024 Sep 25;16(9):e70206. doi: 10.7759/cureus.70206. eCollection 2024 Sep.

Abstract

Background Arteriovenous (AV) shunts are vital for providing long-term vascular access in hemodialysis patients. While brachiocephalic and radiocephalic shunts are commonly employed, data on their primary patency rates and associated complications in resource-limited settings such as Yemen remain scarce. This study aimed to evaluate the primary patency success of AV shunts and identify factors influencing their outcomes in hemodialysis patients at Al-Thawra Modern General Hospital. Methods This prospective observational study was conducted over 28 months, from April 2021 to August 2023, at Al-Thawra Modern General Hospital in Sana'a, Yemen. A total of 163 patients with chronic renal failure requiring AV shunt creation for hemodialysis were included. Data on patient demographics, comorbidities, shunt characteristics, and postoperative outcomes were collected. Primary patency was assessed at the 8-month follow-up interval. Statistical analysis was performed to identify factors associated with shunt patency. Results Among the enrolled 163 patients, the median age was 43.12 years, with 61.3% undergoing brachiocephalic shunt creation. The overall primary patency rate at 8 months was 87.7%, with brachiocephalic shunts exhibiting a significantly greater patency rate (93.0%) than radiocephalic shunts (67.3%) (p = 0.02). Complications occurred in 25% of patients, with pseudoaneurysm formation being the most common complication (6.1%). Factors such as shunt type, patient age, and comorbidities (e.g., diabetes) significantly influence patency outcomes. Conclusion Compared with radiocephalic shunts, brachiocephalic shunts demonstrated superior primary patency rates, suggesting that they may be a preferable option for long-term hemodialysis access in the studied population. These findings emphasize the need for individualized patient management and careful postoperative monitoring, particularly in resource-limited settings such as Yemen, to optimize AV shunt outcomes.

摘要

背景

动静脉(AV)分流术对于为血液透析患者提供长期血管通路至关重要。虽然头臂分流术和桡动脉-头静脉分流术常用,但在也门等资源有限的地区,关于它们的初次通畅率及相关并发症的数据仍然稀少。本研究旨在评估AV分流术的初次通畅成功率,并确定影响也门萨那市阿尔-萨拉现代综合医院血液透析患者AV分流术结局的因素。

方法

本前瞻性观察性研究于2021年4月至2023年8月在也门萨那市的阿尔-萨拉现代综合医院进行了28个月。共纳入163例需要创建AV分流术进行血液透析的慢性肾衰竭患者。收集了患者的人口统计学、合并症、分流术特征及术后结局的数据。在8个月的随访间隔时评估初次通畅情况。进行统计分析以确定与分流术通畅相关的因素。

结果

在纳入的163例患者中,中位年龄为43.12岁,61.3%的患者接受了头臂分流术创建。8个月时的总体初次通畅率为87.7%,头臂分流术的通畅率(93.0%)显著高于桡动脉-头静脉分流术(67.3%)(p = 0.02)。25%的患者发生了并发症,其中假性动脉瘤形成是最常见的并发症(6.1%)。分流术类型、患者年龄和合并症(如糖尿病)等因素显著影响通畅结局。

结论

与桡动脉-头静脉分流术相比,头臂分流术表现出更高的初次通畅率,这表明在研究人群中,头臂分流术可能是长期血液透析通路的更优选择。这些发现强调了个性化患者管理和术后仔细监测的必要性,特别是在也门等资源有限的地区,以优化AV分流术的结局。

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