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慢性血液透析患者长时间久坐发作的各种参数与健康相关生活质量(HRQOL)之间的关系:一项横断面研究。

Relationships Between Various Parameters of Prolonged Sedentary Bouts and Health-Related Quality of Life (HRQOL) in Patients on Chronic Hemodialysis: A Cross-Sectional Study.

作者信息

Sugahara Kentaro, Miyatake Nobuyuki, Kondo Takashi, Namio Keiichi, Hishii Shuhei, Nishi Hiroyuki, Ujike Kazuhiro, Koumoto Kiichi, Suzuki Hiromi, Yamamoto Yorimasa

机构信息

Hygiene, Kagawa University, Miki, JPN.

Physical Therapy, Vocational School Anabuki Rehabilitation College, Takamatsu, JPN.

出版信息

Cureus. 2024 Sep 24;16(9):e70126. doi: 10.7759/cureus.70126. eCollection 2024 Sep.

DOI:10.7759/cureus.70126
PMID:39463640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11502222/
Abstract

BACKGROUND

Previous studies have revealed that sedentary behavior, including quantitative and qualitative parameters, was associated with health-related quality of life (HRQOL) in patients on chronic hemodialysis.

OBJECTIVE

The present study examined the relationships between various parameters of prolonged sedentary bouts on non-hemodialysis days and HRQOL in patients on chronic hemodialysis.

METHODS

A total of 110 patients (47.2%) on chronic hemodialysis (64 men and 46 women, aged 71.4 ± 11.2 years) among 233 patients, who were outpatients at a hospital in Hiroshima prefecture, Japan, were enrolled in this cross-sectional study. Prolonged sedentary bouts were evaluated using a tri-accelerometer, i.e., sedentary behavior (minutes), median sedentary bouts (minutes), maximum sedentary bouts (minutes), sedentary bouts (bouts and minutes/bout), and prolonged sedentary bouts (≥5, ≥10, ≥30, and ≥60 minutes; bouts and minutes/bout). HRQOL was assessed using EuroQol 5-Dimension (EQ-5D).

RESULTS

The EQ-5D score was 0.755 ± 0.216. All prolonged sedentary parameters, except for sedentary bouts (bouts), correlated with HRQOL, and higher correlation coefficients were observed between sedentary behavior (minutes) and HRQOL (r = -0.416) and between maximum sedentary bouts (minutes) and HRQOL (r = -0.436) than between other parameters. These parameters were also identified as factors affecting HRQOL, even after adjustments for confounding factors.

CONCLUSION

In summary, sedentary behavior (minutes) and maximum sedentary bouts (minutes) on non-hemodialysis days, which may be representative of quantitative parameters for sedentary behavior, correlated with HRQOL in patients on chronic hemodialysis.

摘要

背景

先前的研究表明,慢性血液透析患者的久坐行为,包括定量和定性参数,与健康相关生活质量(HRQOL)相关。

目的

本研究探讨了慢性血液透析患者非透析日长时间久坐发作的各种参数与HRQOL之间的关系。

方法

在日本广岛县一家医院的233名门诊患者中,共有110名慢性血液透析患者(47.2%)(64名男性和46名女性,年龄71.4±11.2岁)纳入了这项横断面研究。使用三轴加速度计评估长时间久坐发作,即久坐行为(分钟)、久坐发作中位数(分钟)、久坐发作最长时间(分钟)、久坐发作次数(次数和分钟/次)以及长时间久坐发作(≥5、≥10、≥30和≥60分钟;次数和分钟/次)。使用欧洲五维健康量表(EQ-5D)评估HRQOL。

结果

EQ-5D评分为0.755±0.216。除久坐发作次数(次数)外,所有长时间久坐参数均与HRQOL相关,久坐行为(分钟)与HRQOL之间(r=-0.416)以及久坐发作最长时间(分钟)与HRQOL之间(r=-0.436)的相关系数高于其他参数。即使在调整混杂因素后,这些参数也被确定为影响HRQOL的因素。

结论

总之,非透析日的久坐行为(分钟)和久坐发作最长时间(分钟),这可能是久坐行为定量参数的代表,与慢性血液透析患者的HRQOL相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e246/11502222/8f310abceca0/cureus-0016-00000070126-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e246/11502222/8f310abceca0/cureus-0016-00000070126-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e246/11502222/8f310abceca0/cureus-0016-00000070126-i01.jpg

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本文引用的文献

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Physical activity, sedentary behavior, and the risk of type 2 diabetes: A two-sample Mendelian Randomization analysis in the European population.身体活动、久坐行为与 2 型糖尿病风险:欧洲人群中两样本孟德尔随机化分析。
Front Endocrinol (Lausanne). 2022 Nov 3;13:964132. doi: 10.3389/fendo.2022.964132. eCollection 2022.
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Relation between Prolonged Sedentary Bouts and Health-Related Quality of Life in Patients on Chronic Hemodialysis.
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Acta Med Okayama. 2022 Apr;76(2):113-119. doi: 10.18926/AMO/63404.
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Effect of Underlying Cardiometabolic Diseases on the Association Between Sedentary Time and All-Cause Mortality in a Large Japanese Population: A Cohort Analysis Based on the J-MICC Study.基于 J-MICC 研究的队列分析:潜在心脏代谢疾病对久坐时间与全因死亡率之间关联的影响:一项在大型日本人群中的研究。
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Effects of sedentary behavior and daily walking steps on body mass index and body composition: Prospective observational study using outpatient clinical data of Japanese patients with type 2 diabetes.久坐行为和每日步数对体重指数和身体成分的影响:使用日本 2 型糖尿病门诊临床数据的前瞻性观察研究。
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