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具有挑战性的神经系统表现:恙虫病并发脑膜脑炎及多组颅神经受累

Challenging Neurological Presentation: Scrub Typhus with Meningoencephalitis and Multiple Cranial Nerve Involvement.

作者信息

Biswas Uttam, León-Ruiz Moisés, Shaikh Alamgir, Das Prasenjit, Pal Shyamal Kanti, Ghosh Ritwik, Benito-León Julián

机构信息

Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.

Section of Clinical Neurophysiology, Department of Neurology, University Hospital "La Paz," Madrid, Spain.

出版信息

Neurol Clin Neurosci. 2024 Sep;12(5):316-318. doi: 10.1111/ncn3.12819. Epub 2024 Apr 5.

Abstract

A 40-year-old male farmer from rural West Bengal, India, presented with fever, headaches, seizure, eschar, and palsy of left cranial nerves VII, VIII, IX, and X as a rare clinical manifestation of scrub typhus. Positive IgM enzyme-linked immunosorbent assay tests in serum and cerebrospinal fluid confirmed the diagnosis, with brain magnetic resonance imaging showing meningoencephalitis findings. Treatment with steroids and doxycycline led to neurological improvement. This case highlights the need for heightened clinician awareness towards early detection of scrub typhus's atypical presentations to ensure timely and effective treatment.

摘要

一名来自印度西孟加拉邦农村的40岁男性农民,出现发热、头痛、癫痫发作、焦痂以及左侧颅神经VII、VIII、IX和X麻痹等恙虫病罕见临床表现。血清和脑脊液中IgM酶联免疫吸附试验呈阳性确诊了该病,脑部磁共振成像显示脑膜脑炎表现。使用类固醇和强力霉素治疗后神经症状有所改善。该病例凸显了临床医生需要提高对恙虫病非典型表现早期检测的认识,以确保及时有效的治疗。

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