Ganapathy Thryambak, Villagracia Kirsten Emily M, Kuditini Saharsh S, Sosa Hilario Sorivel
Medicine, American High School, Fremont, USA.
Medicine, Irvington High School, Fremont, USA.
Cureus. 2024 Oct 24;16(10):e72303. doi: 10.7759/cureus.72303. eCollection 2024 Oct.
This case report delves into the case of a patient in the Dominican Republic with multisystem inflammatory syndrome in children (MIS-C). MIS-C is a rare, hyper-inflammatory condition that develops in children as a delayed response to a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, typically appearing with general markers of inflammation such as erythema and, in severe cases, cardiorespiratory symptoms. The three-year-old patient discussed in this report presented with signs of inflammation, such as erythema, rashes, and chapped skin, and reported experiencing diarrhea, vomiting, and fever for multiple days. Notably, a concurrent parasitic presence was found in the patient's fecal sample, and antibiotics were heavily used throughout the course of treatment. We explain the merits and drawbacks behind using antibiotic therapy for MIS-C and suggest steps that clinicians and researchers can take in order to minimize the potential misuse of antibiotics. Specifically, we identify that prioritizing tests for concurrent infections or illnesses is imperative in treating MIS-C patients, and we conclude by stating that using blood cultures and coprological examinations in tandem is an effective strategy for this purpose.
本病例报告深入探讨了多米尼加共和国一名患有儿童多系统炎症综合征（MIS-C）的患者情况。MIS-C是一种罕见的、炎症反应过度的病症，在儿童中作为对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染的延迟反应而出现，通常伴有红斑等炎症的一般体征，严重时会出现心肺症状。本报告中讨论的这名三岁患者出现了炎症迹象，如红斑、皮疹和皮肤皲裂，并报告多日腹泻、呕吐和发烧。值得注意的是，在患者粪便样本中发现了同时存在的寄生虫，并且在整个治疗过程中大量使用了抗生素。我们解释了对MIS-C使用抗生素治疗的优缺点，并提出临床医生和研究人员为尽量减少抗生素潜在滥用情况可采取的措施。具体而言，我们确定在治疗MIS-C患者时优先进行并发感染或疾病的检测至关重要，最后我们指出，同时使用血培养和粪便检查是实现这一目的的有效策略。
