新生儿同种免疫性血小板减少性紫癜：一例病例报告。
Neonatal alloimmune thrombocytopenic purpura: a case report.
作者信息
Deaver J E, Leppert P C, Zaroulis C G
出版信息
Am J Obstet Gynecol. 1986 Jan;154(1):153-5. doi: 10.1016/0002-9378(86)90416-3.
PMID:3946489
Abstract
We report a case of a sibling pair with neonatal alloimmune thrombocytopenic purpura. Serial antepartum platelet alloantibody quantitation by an enzyme-linked immunoabsorbent assay revealed rising antibody titers during advancing gestation. We discuss the implications of this finding in the antepartum diagnosis of neonatal alloimmune thrombocytopenic purpura, a rare, but frequently fatal disorder.
摘要
我们报告了一对患有新生儿同种免疫性血小板减少性紫癜的同胞病例。通过酶联免疫吸附测定法对产前血小板同种抗体进行系列定量分析，结果显示随着孕周增加抗体滴度升高。我们讨论了这一发现对于新生儿同种免疫性血小板减少性紫癜产前诊断的意义，该病虽罕见但往往致命。
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