Dube Suchitra, Hulke Sandip M, Thakare Avinash E, Khadanga Sagar, Wakode Santosh L, Bharshankar Rajay N, Pakhare Abhijit
Physiology Department, AIIMS, Nagpur, Maharashtra, India.
Physiology Department, AIIMS, Bhopal, Madhya Pradesh, India.
J Family Med Prim Care. 2024 Sep;13(9):4094-4098. doi: 10.4103/jfmpc.jfmpc_2035_23. Epub 2024 Sep 11.
Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes; so, a nerve conduction study (NCS) is conducted to detect the type of neuropathy that is present. To discuss the NCS findings in diabetic patients. An observational study was conducted in the Physiology Department of AIIMS, Bhopal, in collaboration with the Medicine Department of the Institute. Seventy-two diagnosed type 2 diabetes mellitus (T2DM) patients were examined using NCS (Nihon Kohden Neuropack XI Machine). Microsoft Excel was utilized for data compilation and result analysis. Based on NCS, 94% of patients were abnormal, and 6% were normal. Of abnormal patients, 89% had asymmetrical involvement, and 5% had symmetrical involvement. About 74% had mixed neuropathy, 11% had motor neuropathy, and 10% had sensory neuropathy. Mixed involvement was seen in 60% of patients and axonal involvement in 35% of patients, and 5% were normal. Lower limb involvement was seen predominately. The most common bilaterally involved motor nerve was the peroneal nerve, seen in 49% of cases, whereas the most common bilaterally involved sensory nerve was the sural nerve involved in 59% of cases. The left tibial nerve was the most common unilaterally involved motor nerve seen in 32% of cases, and the left sural nerve was the most common sensory nerve involved in 54% of cases. Asymmetric sensorimotor involvement with mixed involvement (axonal + demyelinating) was seen in diabetic patients. Peroneal and sural nerves were the most common bilaterally involved motor and sensory nerves, respectively. Similarly, the left tibial and left sural nerves were the most common unilaterally affected motor and sensory nerves, respectively.
糖尿病周围神经病变（DPN）是糖尿病最常见的并发症之一；因此，需进行神经传导研究（NCS）以检测现存的神经病变类型。旨在探讨糖尿病患者的NCS检查结果。在博帕尔全印医学科学研究所生理学系与该研究所医学系合作开展了一项观察性研究。使用NCS（日本光电Neuropack XI机器）对72例确诊的2型糖尿病（T2DM）患者进行了检查。利用Microsoft Excel进行数据汇总和结果分析。根据NCS检查，94%的患者结果异常，6%的患者结果正常。在异常患者中，89%为不对称受累，5%为对称受累。约74%有混合性神经病变，11%有运动神经病变，10%有感觉神经病变。60%的患者有混合性受累，35%的患者有轴索性受累，5%的患者正常。主要为下肢受累。最常见的双侧受累运动神经是腓总神经，见于49%的病例，而最常见的双侧受累感觉神经是腓肠神经，见于59%的病例。左侧胫神经是最常见的单侧受累运动神经，见于32%的病例，左侧腓肠神经是最常见的受累感觉神经，见于54%的病例。糖尿病患者存在不对称性感觉运动受累并伴有混合性受累（轴索性+脱髓鞘性）。腓总神经和腓肠神经分别是最常见的双侧受累运动神经和感觉神经。同样，左侧胫神经和左侧腓肠神经分别是最常见的单侧受累运动神经和感觉神经。
