Kogon D P, Oulton M, Gray J H, Liston R M, Luther E R, Peddle L J, Young D C
Am J Obstet Gynecol. 1986 Feb;154(2):226-30. doi: 10.1016/0002-9378(86)90644-7.
The contents of phosphatidylglycerol and phosphatidylcholine phosphorus in amniotic fluid (10,000 X g pellets) were studied as predictors of fetal lung maturity. The presence of phosphatidylglycerol predicted the absence of neonatal respiratory distress syndrome with 99% probability. When phosphatidylglycerol was absent, phosphatidylcholine phosphorus was a reliable predictor if measured 3 to 7 days before delivery. The probability that respiratory distress syndrome would not occur was 94% when phosphatidylcholine phosphorus was greater than 6. When measurement was performed within 2 days of delivery, the probability that respiratory distress syndrome would not occur fell to 69%. As measured in amniotic fluid, phosphatidylglycerol and phosphatidylcholine phosphorus are reliable antenatal predictors of fetal pulmonary maturity and, therefore, are useful in the management of a number of obstetric conditions.
研究了羊水（10,000 X g沉淀）中磷脂酰甘油和磷脂酰胆碱磷的含量，作为胎儿肺成熟度的预测指标。磷脂酰甘油的存在预测新生儿呼吸窘迫综合征不存在的概率为99%。当不存在磷脂酰甘油时，如果在分娩前3至7天测量，磷脂酰胆碱磷是一个可靠的预测指标。当磷脂酰胆碱磷大于6时，呼吸窘迫综合征不会发生的概率为94%。在分娩后2天内进行测量时，呼吸窘迫综合征不会发生的概率降至69%。如在羊水中所测，磷脂酰甘油和磷脂酰胆碱磷是胎儿肺成熟度可靠的产前预测指标，因此，在许多产科情况的管理中很有用。
