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侵袭性子宫内膜腺癌转移至斜坡的罕见病例:病例说明

An unusual case of aggressive endometrial adenocarcinoma metastasis to the clivus: illustrative case.

作者信息

Sheldon Breanna L, Riordan Katherine, Fallahi Sara, Samargandy Shireen, Le Christopher H, Avery Michael B

机构信息

Departments of Neurosurgery, University of Arizona, Tucson, Arizona.

University of Arizona School of Medicine, Tucson, Arizona.

出版信息

J Neurosurg Case Lessons. 2024 Oct 28;8(18). doi: 10.3171/CASE24392.

Abstract

BACKGROUND

Though endometrial carcinomas are a relatively common cancer of the female genitourinary tract, they rarely metastasize. Similarly, clival metastases make up a tiny fraction of all brain metastases. To the authors' knowledge, an endometrial carcinoma clival metastasis has never been described in the literature; therefore, the authors present the following unusual case of a 69-year-old female with a history of an initially grade 2 endometrial adenocarcinoma that metastasized to her clivus.

OBSERVATIONS

Endometrial carcinoma has the potential to metastasize to the clivus.

LESSONS

Endometrial carcinoma, even when initially low grade, can metastasize intracranially. Prompt diagnosis with tissue biopsy and radiation is the mainstay of treatment, although the prognosis remains poor. https://thejns.org/doi/10.3171/CASE24392.

摘要

背景

虽然子宫内膜癌是女性泌尿生殖道相对常见的癌症,但它们很少发生转移。同样,斜坡转移在所有脑转移中占比极小。据作者所知,文献中从未描述过子宫内膜癌斜坡转移;因此,作者呈现以下这例不同寻常的病例,一名69岁女性,既往有初始为2级的子宫内膜腺癌病史,该肿瘤转移至她的斜坡。

观察结果

子宫内膜癌有可能转移至斜坡。

经验教训

子宫内膜癌即使最初分级较低,也可发生颅内转移。尽管预后仍然很差,但通过组织活检和放疗进行及时诊断是治疗的主要方法。https://thejns.org/doi/10.3171/CASE24392

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