Thörne J, Blomquist S, Elmér O, Jönsson B A, Lindahl S, Strand S E
Am J Surg. 1986 Feb;151(2):216-20. doi: 10.1016/0002-9610(86)90073-5.
Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims.
软组织创伤与血小板在肺部的聚集和滞留有关。这被认为是成人呼吸窘迫综合征后期发展的早期步骤。在本实验中，我们使用一种新的体内血小板滞留动态研究方法，旨在评估软组织创伤对猪肺部血小板捕获的影响以及急性酒精中毒的影响。结果表明，创伤后几分钟内即可观察到显著的肺部血小板捕获，且酒精会显著增加肺部的血小板滞留。这表明酒精中毒的创伤受害者发生创伤后肺部问题的风险增加。
