Department of Applied Chemistry, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Department of Biotechnology, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Mikrochim Acta. 2024 Oct 29;191(11):708. doi: 10.1007/s00604-024-06776-5.
The synthesis and characterization of pH-sensitive boron and nitrogen co-doped CDs (B, N-CDs) is reported. The fluorescence of B, N-CDs exhibited pH-responsive behavior within the range pH 3.0-6.0, attributed to their controlled aggregation and disaggregation. Interestingly, the fluorescence of B, N-CDs was quenched by the inner filter effect from chrome azurol S (CAS). With the subsequent addition of Al, the fluorescence of B, N-CDs was restored due to the formation of blue Al-CAS and B, N-CDs-Al complexes. Consequently, a fluorescent and colorimetric dual-mode sensor for Al detection was developed. The proposed sensor enabled Al detection in the ranges and limits of detection of 3.75-22.5 μM and 2.67 μM for the fluorescent mode and 5-20 μM and 4.8 μM for the colorimetric mode, respectively. Furthermore, the efficacy of the sensor was validated through successful detection of Al in tablet samples. The obtained B, N-CDs promised the application in acid condition and the proposed sensor is expected to be applied to in situ on-line detection of Al.
本文报道了 pH 敏感的硼氮共掺杂 CDs（B，N-CDs）的合成与表征。B，N-CDs 的荧光在 pH 3.0-6.0 范围内表现出 pH 响应行为，这归因于它们的可控聚集和分散。有趣的是，B，N-CDs 的荧光被铬天青 S（CAS）的内滤效应猝灭。随后加入 Al，由于形成蓝色的 Al-CAS 和 B，N-CDs-Al 配合物，B，N-CDs 的荧光恢复。因此，开发了一种用于 Al 检测的荧光和比色双模式传感器。该传感器在荧光模式下的检测范围和检测限分别为 3.75-22.5 μM 和 2.67 μM，在比色模式下的检测范围和检测限分别为 5-20 μM 和 4.8 μM。此外，通过成功检测片剂样品中的 Al，验证了传感器的有效性。所得的 B，N-CDs 有望应用于酸性条件下，所提出的传感器有望应用于 Al 的原位在线检测。
