Gutkind Naomi E, Gedde Steven J
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Curr Opin Ophthalmol. 2025 Mar 1;36(2):140-145. doi: 10.1097/ICU.0000000000001100. Epub 2024 Oct 28.
This review presents guidelines for designing studies and reporting efficacy and safety outcomes in minimally invasive glaucoma surgery (MIGS) research.
Adherence to reporting guidelines in MIGS studies is crucial for providers and patients to appraise surgical options. Recent guidelines have outlined appropriate methodology, efficacy outcomes, and safety reporting, so that study results are presented in an interpretable and uniform manner.
MIGS are changing the glaucoma treatment paradigm by offering safer, less invasive alternatives to traditional filtering surgery. However, inconsistent reporting of outcomes in MIGS trials hampers comparison and clinical decision-making. Recent guidelines have aimed to highlight appropriate methodology and encourage standardization in reporting outcomes to improve the quality of MIGS literature. Key considerations include defining baseline intraocular pressure, reporting standardized demographic data, using consistent endpoints, presenting standardized figures, evaluating medication use, and documenting adverse events. By adhering to these guidelines, MIGS trials can offer clearer insights into surgical outcomes, aiding both surgeons and patients in treatment decisions.
本综述介绍了微创青光眼手术（MIGS）研究中设计研究以及报告疗效和安全性结果的指南。
MIGS研究中遵循报告指南对于医疗服务提供者和患者评估手术选择至关重要。近期指南已概述了适当的方法、疗效结果和安全性报告，以便以可解释且统一的方式呈现研究结果。
MIGS通过提供比传统滤过手术更安全、侵入性更小的替代方案，正在改变青光眼治疗模式。然而，MIGS试验中结果报告不一致妨碍了比较和临床决策。近期指南旨在强调适当的方法，并鼓励在结果报告中实现标准化，以提高MIGS文献的质量。关键考虑因素包括定义基线眼压、报告标准化人口统计学数据、使用一致的终点、呈现标准化图表、评估药物使用以及记录不良事件。通过遵循这些指南，MIGS试验可以更清晰地洞察手术结果，有助于外科医生和患者做出治疗决策。
