Smith R H, Powell G L
Arch Biochem Biophys. 1986 Jan;244(1):357-60. doi: 10.1016/0003-9861(86)90124-4.
The critical micelle concentration (CMC) of a series of saturated fatty acyl-CoAs have been determined using a fluorescent titration method with 2-toluidinylnaphthalene-6-sulfonate as a probe. The CMC was found to be a function of the number of carbon atoms in the acyl chain over the range tested (12 to 18). A double bond has the effect on the CMC of decreasing the acyl chain by 1.6 carbon atoms. Knowledge that the CMC of each of these fatty acyl-CoAs is a function of the acyl chain length and the availability of a simple and appropriate method for the estimation of this property under other conditions should be of importance in designing and interpreting in vitro experiments with these compounds.
使用以2-甲苯胺基萘-6-磺酸盐为探针的荧光滴定法测定了一系列饱和脂肪酰辅酶A的临界胶束浓度（CMC）。在所测试的范围内（12至18个碳原子），发现CMC是酰基链中碳原子数的函数。双键对CMC有影响，使酰基链减少1.6个碳原子。了解这些脂肪酰辅酶A的CMC是酰基链长度的函数，以及在其他条件下有简单合适的方法来估算该性质，对于设计和解释使用这些化合物的体外实验应该具有重要意义。
