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运动疗法和乳腺癌手术后的生活质量:系统评价与荟萃分析。

Kinesiotherapy and Quality of Life after Breast Cancer Surgery: A Systematic Review with Meta-analysis.

机构信息

Department of Medicine, Post-Graduation Program in Health Sciences, Federal University of Goiás (UFG), Goiânia, GO, Brazil.

Centro Avançado de Diagnóstico da Mama (CORA), Teaching Hospital, Federal University of Goiás (UFG), Goiânia, GO, Brazil.

出版信息

Asian Pac J Cancer Prev. 2024 Oct 1;25(10):3341-3347. doi: 10.31557/APJCP.2024.25.10.3341.

DOI:10.31557/APJCP.2024.25.10.3341
PMID:39471000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11711346/
Abstract

OBJECTIVE

To determine whether kinesiotherapy improves the quality of life of women with breast cancer following surgery.

METHODS

This meta-analysis was conducted according to the Cochrane and PRISMA recommendations. A search was conducted of the PubMed, Cochrane, and the Virtual Health Library Regional Portal databases to identify randomized and observational studies that compared the performance versus non-performance of kinesiotherapy protocols in patients who had undergone breast cancer surgery. The outcomes evaluated were overall health status, physical functioning, emotional functioning, and social functioning. Statistical analyses were conducted using RevMan version 5.4.1. Heterogeneity was evaluated using the I2 statistic.

RESULTS

Twelve studies with a total of 867 patients were included. Of these, 669 women (77.2%) underwent mastectomy. Five studies conducted a before-after evaluation and seven studies evaluated intervention versus non-intervention in two different groups. Of the outcomes evaluated, overall health status (standardized mean difference [SMD] 0.45; 95%CI: 0.09-0.82; p=0.01; I2=75%), physical functioning (SMD 0.89; 95%CI: 0.39-1.39; p=0.0005; I2=91%), social functioning (0.67; 95%CI: 0.26-1.09; p=0.001; I2=89%) and emotional functioning (SMD 0.90; 95%CI: 0.40-1.40; p=0.0004; I2=92%) showed significant results in favor of kinesiotherapy.

CONCLUSION

Kinesiotherapy had a positive effect on the outcomes of overall health status and physical, social, and emotional functioning compared to controls. Therefore, kinesiotherapy appears to help recover quality of life in patients submitted to surgery for breast cancer.

摘要

目的

确定运动疗法是否能提高乳腺癌术后女性的生活质量。

方法

本荟萃分析根据 Cochrane 和 PRISMA 建议进行。检索 PubMed、Cochrane 和 Virtual Health Library Regional Portal 数据库,以确定比较乳腺癌手术后患者进行运动疗法与不进行运动疗法的随机和观察性研究。评估的结局包括总体健康状况、身体功能、情绪功能和社会功能。使用 RevMan 版本 5.4.1 进行统计学分析。使用 I2 统计量评估异质性。

结果

共纳入 12 项研究,总计 867 名患者。其中 669 名女性(77.2%)接受了乳房切除术。5 项研究进行了前后评估,7 项研究在两组中评估了干预与非干预。在评估的结局中,总体健康状况(标准化均数差 [SMD] 0.45;95%CI:0.09-0.82;p=0.01;I2=75%)、身体功能(SMD 0.89;95%CI:0.39-1.39;p=0.0005;I2=91%)、社会功能(0.67;95%CI:0.26-1.09;p=0.001;I2=89%)和情绪功能(SMD 0.90;95%CI:0.40-1.40;p=0.0004;I2=92%)均显示运动疗法有显著获益。

结论

与对照组相比,运动疗法对总体健康状况以及身体、社会和情绪功能的结局有积极影响。因此,运动疗法似乎有助于恢复乳腺癌手术患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/f51ffb304793/APJCP-25-3341-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/e082ab4ca8a0/APJCP-25-3341-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/11d6701bac4d/APJCP-25-3341-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/9adf1f9a819b/APJCP-25-3341-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/b3a75407e7bd/APJCP-25-3341-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/f51ffb304793/APJCP-25-3341-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/e082ab4ca8a0/APJCP-25-3341-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/11d6701bac4d/APJCP-25-3341-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/9adf1f9a819b/APJCP-25-3341-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/b3a75407e7bd/APJCP-25-3341-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2243/11711346/f51ffb304793/APJCP-25-3341-g005.jpg

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The Effectiveness of an Upper Limb Rehabilitation Program on Quality of Life in Breast Cancer Patients after Mastectomy: A Randomized Controlled Trial.上肢康复方案对乳腺癌根治术后患者生活质量的影响:一项随机对照试验。
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