Dillon T, Berman W, Yabek S M, Seigel R, Akl B, Wernly J
Ann Thorac Surg. 1986 Feb;41(2):146-9. doi: 10.1016/s0003-4975(10)62655-0.
Severe superior vena caval (SVC) obstruction following the Mustard operation resulted in substantially increased intracranial pressure in 3 patients. A pathophysiological mechanism is postulated to explain the cerebral edema in 1 and the communicating hydrocephalus in 2. Following surgical relief of the obstruction in the latter 2, there was a decrease in both the rate of head growth and the ventricular size. It is of note that despite the angiographic appearance of azygous decompression, the pressure elevation from the SVC obstruction was transmitted to the brain. The long-term follow-up at three and four years of the 2 infants with communicating hydrocephalus suggests that aggressive treatment is compatible with a favorable outcome.
在Mustard手术后发生严重的上腔静脉（SVC）梗阻，导致3例患者颅内压大幅升高。推测了一种病理生理机制来解释1例患者的脑水肿和2例患者的交通性脑积水。在后2例患者手术解除梗阻后，头围生长速率和脑室大小均减小。值得注意的是，尽管血管造影显示奇静脉减压，但SVC梗阻导致的压力升高仍传递至脑部。对2例交通性脑积水婴儿进行的3年和4年长期随访表明，积极治疗可带来良好预后。
