Dal Pont Christian S, Argenta Fábio, Bezerra Rodrigo, Viana Gustavo M, Starke Siegmar, Azevedo Guilherme S A, Mota-Gomes Marco A, Barroso Weimar S, Miranda Roberto D, Barbosa Eduardo C D, Brandão Andréa A, Feitosa Camila L D M, Gonçalves Thales A T, Nobre Fernando, Mion Decio, Sposito Andrei C, Feitosa Audes D M, Nadruz Wilson
Department of Internal Medicine, School of Medical Sciences, State University of Campinas, Campinas, SP, Brazil.
Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco, Recife, PE, Brazil.
Hypertens Res. 2025 Jan;48(1):398-401. doi: 10.1038/s41440-024-01973-4. Epub 2024 Oct 29.
This study investigated the prevalence of white-coat hypertension (WCH) among individuals with office isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic-diastolic hypertension (SDH). We evaluated 9122 individuals [57.0 ± 14.5 years, 51% men] with office blood pressure ≥140/90 mmHg who underwent ambulatory blood pressure monitoring (ABPM) and were categorized into younger (<40-years), middle-aged (≥40 and <60-years) and older (≥60-years) groups. The prevalence of WCH in SDH, ISH, and IDH was 18, 61, and 37% in younger, 16, 55, and 29% in middle-aged, and 23, 51, and 40% in older individuals. Multivariable logistic regression analysis showed a higher likelihood of WCH in ISH (4.1, 3.6, and 2.1-fold all p < 0.001) and IDH (1.9, 1.5, and 1.5-fold; all p < 0.001) compared to SDH among younger, middle-aged and older individuals, respectively. These data indicate that ISH and, to a minor extent, IDH are linked to a higher prevalence of WCH derived from ABPM exams.
本研究调查了单纯诊室收缩期高血压（ISH）、单纯舒张期高血压（IDH）和收缩期-舒张期高血压（SDH）患者中白大衣高血压（WCH）的患病率。我们评估了9122例患者[年龄57.0±14.5岁，男性占51%]，其诊室血压≥140/90 mmHg，接受了动态血压监测（ABPM），并被分为年轻组（<40岁）、中年组（≥40岁且<60岁）和老年组（≥60岁）。SDH、ISH和IDH患者中WCH的患病率在年轻组分别为18%、61%和37%，中年组分别为16%、55%和29%，老年组分别为23%、51%和40%。多变量逻辑回归分析显示，与SDH相比，年轻、中年和老年个体中ISH（分别为4.1倍、3.6倍和2.1倍，均p<0.001）和IDH（分别为1.9倍、1.5倍和1.5倍；均p<0.001）患者发生WCH的可能性更高。这些数据表明，ISH以及在较小程度上IDH与ABPM检查中较高的WCH患病率相关。
