伴有牙源性角化囊肿的原发性牙源性肿瘤的组织病理学谱：世界上 1 例报道病例，并提出了“更新的诊断标准”。
Histopathological spectrum of primordial odontogenic tumor with co-existing dentigerous cyst: 1 reported case of the world with a proposed 'updated diagnostic criteria'.
机构信息
Department of Dental Medicine, College of Medicine and Health Sciences, Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia.
Department of Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, India.
出版信息
Diagn Pathol. 2024 Oct 29;19(1):143. doi: 10.1186/s13000-024-01560-8.
BACKGROUND
POT is a relatively newly described benign odontogenic tumor with very few cases registered to date. We present the 1st case of Primordial odontogenic tumor (POT) from Sub-Saharan Africa with unique clinicopathological features; also, this is the first case to report POT's existence as a Hybrid Odontogenic lesion (HOL), with a pertinent review of the literature.
CASE PRESENTATION
This was a 17-year-old patient who presented with slow-growing, painless posterior mandibular swelling. The imaging revealed a well-defined, unilocular, expansile, lytic lesion with internal calcific foci surrounding an impacted #36, indicating a calcifying odontogenic cyst. The incisional biopsy revealed the presence of POT. The tumor was excised along with the involved tooth.
CONCLUSION
POT is predominantly a non-aggressive and mostly affects the pediatric population. Hence, clinicians must be updated on all the aspects of this tumor to diagnose it appropriately and avoid any undue over-or under-treatment.
背景
POT 是一种相对较新描述的良性牙源性肿瘤，迄今为止登记的病例非常少。我们报告了首例来自撒哈拉以南非洲的原始牙源性肿瘤（POT），具有独特的临床病理特征；此外，这也是首例报告 POT 作为混合性牙源性病变（HOL）存在的病例，并对文献进行了相关回顾。
病例介绍
这是一名 17 岁的患者，表现为缓慢生长、无痛性下颌后牙区肿胀。影像学检查显示一个界限清楚、单房性、膨胀性、溶骨性病变，内部有钙化灶，围绕着一颗埋伏的#36，提示为牙源性钙化囊肿。切开活检显示存在 POT。肿瘤连同受累牙齿被切除。
结论
POT 主要为非侵袭性，多发生于儿童。因此，临床医生必须了解该肿瘤的所有方面，以便进行适当诊断，避免过度或不足治疗。
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