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原始牙源性肿瘤:1例新病例报告及文献复习

Primordial Odontogenic Tumor: Report of a New Case and Literature Review.

作者信息

Bomfim Bianca Bravim, Prado Roberto, Sampaio Renato Kobler, Conde Danielle Castex, de Andrade Bruno Augusto Benevenuto, Agostini Michelle, Romañach Mário José

机构信息

Oral Surgery, Fluminense Federal University (UFF), Niterói, Brazil.

Oral Surgery, School of Dentistry, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.

出版信息

Head Neck Pathol. 2019 Jun;13(2):125-130. doi: 10.1007/s12105-018-0913-7. Epub 2018 Mar 19.

Abstract

Primordial odontogenic tumor (POT) was recently recognized in the 2017 World Health Organization (WHO) Classification as a distinct mixed odontogenic tumor most commonly observed in the posterior mandible of young patients. POT appears as an expansile radiolucency associated to an unerupted tooth. The aim of the present study was to perform a retrospective microscopic evaluation of pediatric odontogenic tumors diagnosed in an Oral Pathology Laboratory from Rio de Janeiro-Brazil, in order to reclassify potential cases as POT. From 150 cases of odontogenic tumors in children diagnosed in the last 50 years, one case filled the criteria for POT, being therefore better diagnosed as such. The patient was in the first decade of life and presented a well-defined expansile tumor in the posterior mandible, which had been initially diagnosed as immature complex odontoma. To the best of our knowledge, only 12 cases of POT have been reported in the English-language literature. We herein present an additional case of POT and review of its clinicopathological findings is offered.

摘要

原始牙源性肿瘤(POT)最近在2017年世界卫生组织(WHO)分类中被确认为一种独特的混合性牙源性肿瘤,最常见于年轻患者的下颌后部。POT表现为与未萌出牙齿相关的膨胀性透射区。本研究的目的是对巴西里约热内卢一家口腔病理实验室诊断的儿童牙源性肿瘤进行回顾性显微镜评估,以便将潜在病例重新分类为POT。在过去50年诊断的150例儿童牙源性肿瘤病例中,有1例符合POT标准,因此被更好地诊断为此类。该患者处于生命的第一个十年,下颌后部出现一个边界清晰的膨胀性肿瘤,最初被诊断为不成熟复合性牙瘤。据我们所知,英文文献中仅报道了12例POT。我们在此报告另外1例POT,并对其临床病理表现进行回顾。

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本文引用的文献

2
Primordial odontogenic tumour: report of two cases.
Histopathology. 2018 Jun;72(7):1221-1227. doi: 10.1111/his.13488. Epub 2018 Mar 15.
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Primordial Odontogenic Tumor: A case report with histopathological analyses.
Pathol Int. 2017 Dec;67(12):638-643. doi: 10.1111/pin.12601. Epub 2017 Nov 1.
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A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017).
Pathol Int. 2017 Jul;67(7):365-369. doi: 10.1111/pin.12543. Epub 2017 May 25.
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Primordial Odontogenic Tumor: Report of a Case.
J Oral Maxillofac Surg. 2016 Mar;74(3):547-51. doi: 10.1016/j.joms.2015.08.019. Epub 2015 Sep 18.

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