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Modulating GSK3β Phosphorylation: Bio-Corona Protective Effects Against Silica Nanoparticle-Induced Neurotoxicity.

作者信息

Qiao Xin, Cui Xuejing, Chen Chunying

机构信息

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.

University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Environ Health (Wash). 2024 Jan 30;2(2):62-64. doi: 10.1021/envhealth.4c00002. eCollection 2024 Feb 16.

DOI:10.1021/envhealth.4c00002

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11504453/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6611/11504453/faef06bf9823/eh4c00002_0001.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6611/11504453/faef06bf9823/eh4c00002_0001.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6611/11504453/faef06bf9823/eh4c00002_0001.jpg

相似文献

[1]

Modulating GSK3β Phosphorylation: Bio-Corona Protective Effects Against Silica Nanoparticle-Induced Neurotoxicity.

Environ Health (Wash). 2024-1-30

[2]

Silica Nanoparticle Exposure Caused Brain Lesion and Underlying Toxicological Mechanism: Route-Dependent Bio-Corona Formation and GSK3β Phosphorylation Status.

Environ Health (Wash). 2023-11-8

[3]

A nano-bio interfacial protein corona on silica nanoparticle.

Colloids Surf B Biointerfaces. 2018-4-8

[4]

Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.

Am J Physiol Renal Physiol. 2005-4

[5]

Lithium protects against methamphetamine-induced neurotoxicity in PC12 cells via Akt/GSK3β/mTOR pathway.

Biochem Biophys Res Commun. 2015-9-25

[6]

A hypothetic role of minocycline as a neuroprotective agent against methylphenidate-induced neuronal mitochondrial dysfunction and tau protein hyper-phosphorylation: Possible role of PI3/Akt/GSK3β signaling pathway.

Med Hypotheses. 2019-4-24

[7]

Coronal ApoE Protein Combines with LRP1 to Inactivate GSK3β That Mitigates Silica Nanoparticle-Induced Brain Lesion.

ACS Chem Neurosci. 2024-2-21

[8]

Role of Physicochemical Properties of Protein in Modulating the Nanoparticle-Bio Interface.

J Biomed Nanotechnol. 2020-8-1

[9]

Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3β.

Neurochem Int. 2011-6-6

[10]

C-Glycosylflavones Alleviate Tau Phosphorylation and Amyloid Neurotoxicity through GSK3β Inhibition.

ACS Chem Neurosci. 2016-7-20

本文引用的文献

[1]

The blood-brain barrier: structure, regulation, and drug delivery.

Signal Transduct Target Ther. 2023-5-25

[2]

Dynamic intracellular exchange of nanomaterials' protein corona perturbs proteostasis and remodels cell metabolism.

Proc Natl Acad Sci U S A. 2022-6-7

[3]

Serum apolipoprotein A-I depletion is causative to silica nanoparticles-induced cardiovascular damage.

Proc Natl Acad Sci U S A. 2021-11-2

[4]

The Underlying Function and Structural Organization of the Intracellular Protein Corona on Graphdiyne Oxide Nanosheet for Local Immunomodulation.

Nano Lett. 2021-7-28

[5]

Environmental dimensions of the protein corona.

Nat Nanotechnol. 2021-6

[6]

Strategies for delivering therapeutics across the blood-brain barrier.

Nat Rev Drug Discov. 2021-5

[7]

Molybdenum derived from nanomaterials incorporates into molybdenum enzymes and affects their activities in vivo.

Nat Nanotechnol. 2021-6

[8]

Current understanding of biological identity at the nanoscale and future prospects.

Nat Nanotechnol. 2021-3

[9]

A framework for designing delivery systems.

Nat Nanotechnol. 2020-10

[10]

Protein Corona-Enabled Systemic Delivery and Targeting of Nanoparticles.

AAPS J. 2020-6-3

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