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V2型特发性三叉神经痛患者微血管减压术与经皮球囊压迫术疗效比较

Comparison of microvascular decompression and percutaneous balloon compression efficacy in patients with V2 idiopathic trigeminal neuralgia.

作者信息

Ji Ye, Wang Junwu

机构信息

Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.

出版信息

Front Neurol. 2024 Oct 15;15:1406602. doi: 10.3389/fneur.2024.1406602. eCollection 2024.

Abstract

OBJECTIVE

This study aims to compare the efficacy and long-term prognosis of microvascular decompression (MVD) versus percutaneous balloon compression (PBC) in patients with idiopathic V2 (maxillary branch) trigeminal neuralgia.

METHODS

We retrospectively analyzed the clinical information and follow-up data of patients who underwent surgical treatment for V2 idiopathic trigeminal neuralgia from January 2020 to January 2023. A total of 58 patients were included in the MVD group and 99 in the PBC group. All surgeries were performed by two physicians at the same center, with follow-up conducted by a separate, trained researcher. We compared the initial versus 12-month postoperative pain relief rates (scored using the BNI), surgical complications, and described pain relief rates after long-term follow-up in both groups using Kaplan-Meier analysis.

RESULTS

The study included a total of 157 patients (MVD 58, PBC 99). The median age of patients in the MVD group was lower than that in the PBC group (58 [51-65] vs. 63 [58-69],  = 0.002). There was no significant difference between the two groups in terms of pain relief rates initially after surgery and at 12 months ( = 0.521,  = 0.713). However, the MVD group had significantly better outcomes regarding postoperative facial numbness ( < 0.0001), masticatory weakness ( = 0.0017), and other complications ( = 0.04). Kaplan-Meier analysis showed that MVD provided a longer duration of pain relief than PBC ( = 0.0323), with most recurrences in both groups occurring within 1-2 years after surgery.

CONCLUSION

There were no significant differences in significant pain relief rates between the two groups initially after surgery and at 12 months. However, the MVD group showed a clear advantage over PBC regarding postoperative facial numbness, masticatory weakness, and other complications; moreover, Kaplan-Meier analysis revealed that MVD offers a longer duration of pain relief for patients.

摘要

目的

本研究旨在比较微血管减压术(MVD)与经皮球囊压迫术(PBC)治疗特发性V2(上颌支)三叉神经痛患者的疗效及长期预后。

方法

我们回顾性分析了2020年1月至2023年1月接受V2特发性三叉神经痛手术治疗患者的临床信息和随访数据。MVD组纳入58例患者,PBC组纳入99例患者。所有手术均由同一中心的两名医生进行,由另一名经过培训的研究人员进行随访。我们比较了术后初始与12个月时的疼痛缓解率(使用BNI评分)、手术并发症,并使用Kaplan-Meier分析描述了两组长期随访后的疼痛缓解率。

结果

该研究共纳入157例患者(MVD组58例,PBC组99例)。MVD组患者的中位年龄低于PBC组(58[51 - 65]岁 vs. 63[58 - 69]岁,P = 0.002)。两组术后初始及12个月时的疼痛缓解率无显著差异(P = 0.521,P = 0.713)。然而,MVD组在术后面部麻木(P < 0.0001)、咀嚼肌无力(P = 0.0017)及其他并发症(P = 0.04)方面的结局明显更好。Kaplan-Meier分析显示,MVD的疼痛缓解持续时间比PBC长(P = 0.0323),两组大多数复发发生在术后1 - 2年内。

结论

两组术后初始及12个月时的显著疼痛缓解率无显著差异。然而,MVD组在术后面部麻木、咀嚼肌无力及其他并发症方面比PBC组具有明显优势;此外,Kaplan-Meier分析显示,MVD为患者提供了更长的疼痛缓解持续时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3270/11518807/58cd067777de/fneur-15-1406602-g001.jpg

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