Ju Zhi-Heng, Wang Mei-Ju
Department of Ophthalmology, The Third People's Hospital of Changzhou, Changzhou 213001, Jiangsu Province, China.
World J Psychiatry. 2024 Oct 19;14(10):1513-1520. doi: 10.5498/wjp.v14.i10.1513.
As the incidence of diabetes continues to increase, the number of patients with diabetic retinopathy (DR) also increases each year. After undergoing vitrectomy for DR, patients often experience negative emotional problems that negatively affect their recovery.
To investigate negative feelings in patients with DR after vitrectomy and to explore related influencing factors.
A total of 146 individuals with DR who were accepted for treatment at The Third People's Hospital of Changzhou from May 2021 to April 2023 were recruited to participate in this study. All patients underwent vitrectomy. The self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were used to assess the degree of anxiety and depression 2-3 days after the operation. The participants were divided into a healthy control group and a negative emotion group. The patients' general demographic characteristics and blood glucose levels were collected. Logistic regression analysis was used to analyze the factors influencing negative feelings post-operation. Pearson's correlation coefficient was used to analyze the association between SAS scores, SDS scores, and blood glucose levels.
The control group included 85 participants. The negative emotion group comprised 40 participants with anxiety, 13 with depression, and eight with both. Logistic regression showed that being female (OR = 3.090, 95%CI: 1.217-7.847), a family per capita monthly income of < 5000 yuan (OR = 0.337, 95%CI: 0.165-0.668), and a longer duration of diabetes (OR = 2.068, 95%CI: 1.817-3.744) were risk factors for negative emotions in patients with DR after vitrectomy ( < 0.05). The concentrations of fasting plasma glucose (FPG), 2-hour postprandial glucose (2hPG), and glycated hemoglobin (HbA1c) in the negative emotion group exceeded those in the control group ( < 0.05). SAS scores were positively associated with FPG ( = 0.422), 2hPG ( = 0.334), and HbA1c ( = 0.362; < 0.05). SDS scores were positively correlated with FPG ( = 0.218) and 2hPG ( = 0.218; < 0.05).
Sex, income level, and duration of diabetes were factors that influenced negative emotions post-vitrectomy. Negative emotions were positively correlated with blood glucose levels, which can be used to develop intervention strategies.
随着糖尿病发病率持续上升，糖尿病视网膜病变（DR）患者数量也逐年增加。DR患者接受玻璃体切除术后，常出现负面情绪问题，对其康复产生不利影响。
调查DR患者玻璃体切除术后的负面情绪，并探究相关影响因素。
选取2021年5月至2023年4月在常州市第三人民医院接受治疗的146例DR患者参与本研究。所有患者均接受了玻璃体切除术。采用焦虑自评量表（SAS）和抑郁自评量表（SDS）评估术后2 - 3天的焦虑和抑郁程度。将参与者分为健康对照组和负面情绪组。收集患者的一般人口学特征和血糖水平。采用Logistic回归分析影响术后负面情绪的因素。采用Pearson相关系数分析SAS评分、SDS评分与血糖水平之间的关联。
对照组有85名参与者。负面情绪组包括40例焦虑患者、13例抑郁患者和8例兼具焦虑和抑郁的患者。Logistic回归显示，女性（OR = 3.090，95%CI：1.217 - 7.847）、家庭人均月收入<5000元（OR = 0.337，95%CI：0.165 - 0.668）以及糖尿病病程较长（OR = 2.068，95%CI：1.817 - 3.744）是DR患者玻璃体切除术后出现负面情绪的危险因素（<0.05）。负面情绪组的空腹血糖（FPG）、餐后2小时血糖（2hPG）和糖化血红蛋白（HbA1c）浓度均高于对照组（<0.05）。SAS评分与FPG（= 0.422）、2hPG（= 0.334）和HbA1c（= 0.362；<0.05）呈正相关。SDS评分与FPG（= 0.218）和2hPG（= 0.218；<0.05）呈正相关。
性别、收入水平和糖尿病病程是影响玻璃体切除术后负面情绪的因素。负面情绪与血糖水平呈正相关，可据此制定干预策略。
