Valentin N, Lomholt B, Jensen J S, Hejgaard N, Kreiner S
Br J Anaesth. 1986 Mar;58(3):284-91. doi: 10.1093/bja/58.3.284.
The mortality following surgical correction of upper femoral fractures was investigated in 578 patients, over the age of 50 yr, randomly allocated to receive spinal (bupivacaine) or general (enflurane or neurolept) anaesthesia. Thirty days after surgery the mortality was 6% after spinal and 8% after general anaesthesia (ns). Six months to 2 years after surgery the mortality was identical in the two groups. There were no differences with respect to ambulation and discharge. The estimated blood loss was smaller (P less than 0.05) in patients receiving spinal anaesthesia. Regardless of the anaesthetic technique, a high short-term mortality was related to age, male sex, and trochanteric fracture, whereas excess long-term mortality was related to male sex and high ASA scores.
对578例年龄超过50岁的股骨上段骨折手术矫正患者进行了研究,这些患者被随机分配接受脊髓麻醉(布比卡因)或全身麻醉(恩氟烷或神经安定镇痛)。术后30天,脊髓麻醉组死亡率为6%,全身麻醉组为8%(无统计学差异)。术后6个月至2年,两组死亡率相同。在行走和出院方面没有差异。接受脊髓麻醉的患者估计失血量较少(P<0.05)。无论采用何种麻醉技术,短期高死亡率与年龄、男性性别和转子间骨折有关,而长期高死亡率与男性性别和高ASA评分有关。