Suppr超能文献

一名患有痉挛性脑瘫的女性在接受鞘内注射巴氯芬治疗期间连续怀孕三次。

Three consecutive pregnancies in a woman with spastic cerebral palsy being treated with intrathecal baclofen therapy.

作者信息

Barker Kim D D, Murtuza M Imran, Sloan Ellen V

机构信息

Department of Physical Medicine and Rehabilitation, UT Southwestern Medical Center, Dallas, Texas, USA.

Department of Physical Medicine and Rehabilitation, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Int J Gynaecol Obstet. 2025 Mar;168(3):893-895. doi: 10.1002/ijgo.15988. Epub 2024 Oct 30.

Abstract

Baclofen is a commonly used medication for spasticity in patients with an injury to the central nervous system. For some, intrathecal delivery of baclofen provides better treatment with fewer systemic side effects. Baclofen is a category C medication during pregnancy based on animal studies. This narrative review presents the three consecutive pregnancies of a woman with spastic quadriparesis due to cerebral palsy that was being treated with an intrathecal baclofen (ITB) pump. Her spasticity care occurred at a large academic institution. Her prenatal and perinatal care occurred at the adjacent county hospital. There is limited literature on the safety of the use of an ITB pump for the treatment of spasticity in pregnant women, and this patient presentation aims to describe the course for the mother and her infants as she received treatment for her spasticity with an ITB pump.

摘要

巴氯芬是治疗中枢神经系统损伤患者痉挛的常用药物。对于一些患者,鞘内注射巴氯芬能提供更好的治疗效果,且全身副作用更少。基于动物研究,巴氯芬在孕期属于C类药物。本叙述性综述介绍了一名因脑瘫导致痉挛性四肢瘫的女性连续三次怀孕的情况,她正在接受鞘内巴氯芬(ITB)泵治疗。她的痉挛治疗在一家大型学术机构进行。她的产前和围产期护理在相邻的县医院进行。关于使用ITB泵治疗孕妇痉挛安全性的文献有限,本病例介绍旨在描述这位母亲及其婴儿在接受ITB泵治疗痉挛期间的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e166/11823320/3aa38a65d767/IJGO-168-893-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验