Barker Kim D D, Murtuza M Imran, Sloan Ellen V
Department of Physical Medicine and Rehabilitation, UT Southwestern Medical Center, Dallas, Texas, USA.
Department of Physical Medicine and Rehabilitation, Emory University School of Medicine, Atlanta, Georgia, USA.
Int J Gynaecol Obstet. 2025 Mar;168(3):893-895. doi: 10.1002/ijgo.15988. Epub 2024 Oct 30.
Baclofen is a commonly used medication for spasticity in patients with an injury to the central nervous system. For some, intrathecal delivery of baclofen provides better treatment with fewer systemic side effects. Baclofen is a category C medication during pregnancy based on animal studies. This narrative review presents the three consecutive pregnancies of a woman with spastic quadriparesis due to cerebral palsy that was being treated with an intrathecal baclofen (ITB) pump. Her spasticity care occurred at a large academic institution. Her prenatal and perinatal care occurred at the adjacent county hospital. There is limited literature on the safety of the use of an ITB pump for the treatment of spasticity in pregnant women, and this patient presentation aims to describe the course for the mother and her infants as she received treatment for her spasticity with an ITB pump.
巴氯芬是治疗中枢神经系统损伤患者痉挛的常用药物。对于一些患者，鞘内注射巴氯芬能提供更好的治疗效果，且全身副作用更少。基于动物研究，巴氯芬在孕期属于C类药物。本叙述性综述介绍了一名因脑瘫导致痉挛性四肢瘫的女性连续三次怀孕的情况，她正在接受鞘内巴氯芬（ITB）泵治疗。她的痉挛治疗在一家大型学术机构进行。她的产前和围产期护理在相邻的县医院进行。关于使用ITB泵治疗孕妇痉挛安全性的文献有限，本病例介绍旨在描述这位母亲及其婴儿在接受ITB泵治疗痉挛期间的情况。
