Connected Content, Ltd., Boulder, CO.
University of Florida College of Pharmacy, Gainesville.
J Manag Care Spec Pharm. 2024 Nov;30(11-a Suppl):S1-S9. doi: 10.18553/jmcp.2024.30.11-a.s1.
Wet age-related macular degeneration (AMD) is an acquired degeneration of the retina that can lead to central vision impairment. It is primarily treated with intravitreal injections of vascular endothelial growth factor inhibitors. Although vascular endothelial growth factor inhibitors can effectively prevent progression of vision loss in many patients, they require ongoing regular administration and are therefore associated with considerable treatment burden. To gain insights into the impact of wet AMD and its treatment, AMCP convened an expert panel of managed care stakeholders in April 2024 through its Market Insights program. Key issues related to wet AMD identified by participants included cost and affordability, provider-related considerations, biosimilar adoption, measuring and improving quality, and incorporating the patient voice. Suggested payer best practices related to these issues in wet AMD also emerged from the discussion.
湿性年龄相关性黄斑变性(AMD)是一种视网膜获得性变性,可导致中心视力损害。它主要通过玻璃体内注射血管内皮生长因子抑制剂进行治疗。尽管血管内皮生长因子抑制剂可以有效预防许多患者视力丧失的进展,但它们需要持续定期给药,因此与相当大的治疗负担相关。为了深入了解湿性 AMD 及其治疗的影响,AMCP 通过其市场洞察计划于 2024 年 4 月召集了一个管理式医疗利益相关者专家组。参与者确定的与湿性 AMD 相关的关键问题包括成本和负担能力、与提供者相关的考虑因素、生物类似药的采用、衡量和提高质量,以及纳入患者的意见。讨论还提出了与湿性 AMD 相关问题的支付方最佳实践建议。