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肯尼亚成年艾滋病毒感染者中的高血压发病率。

Incidence of high blood pressure among Kenyan adults with HIV.

作者信息

Suvada Kara, Kocher Erica, Diwan Nazha, Nagy Andrew, Nderitu Mary, Kibaara Charles, Ngomoa Richard, Cagle Tony J, Kariuki Jacob, Wall Kristin M, Brunissen Ludivine, Ramireddy Shashank, Johnson Leslie C M, Chung Michael H, Ali Mohammed K

机构信息

Department of Epidemiology, Rollins School of Public Health, Emory University.

Emory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University.

出版信息

AIDS. 2025 Mar 1;39(3):281-289. doi: 10.1097/QAD.0000000000004050. Epub 2024 Oct 29.

Abstract

OBJECTIVE

People with HIV (PWH) face a heightened risk of cardiovascular diseases, partly because of increased high blood pressure risk. This study assessed high blood pressure burden (i.e. incidence and prevalence) among PWH in Kenya over time.

DESIGN

Longitudinal, open cohort study.

METHODS

We estimated the incidence and prevalence of high blood pressure in a large sample of Kenyans with HIV from the Coptic Hope Center using electronic medical records from 2004 to 2023. We defined incident high blood pressure as first visit after baseline at which each patient had a SBP at least 140 mmHg and/or a DBP at least 90 mmHg.

RESULTS

Our sample included 38 709 PWH seeking care at Coptic Hope Center clinics in Kenya (2004-2023). Nearly 40% of patients had high blood pressure at first visit. Among the 60% of patients initially normotensive, almost 40% developed high blood pressure within 20 years. The yearly prevalence of high blood pressure ranged from 8 to 58%. Average SBP was higher among patients who had their first visit from 2019 to 2023 compared with those visiting in the early 2000s and 2010s.

CONCLUSION

Our findings reveal a high and rising burden of high blood pressure among PWH in a large, faith-based health system in Kenya. This underscores the need for stronger integration of care for individuals with concurrent HIV, high blood pressure, and other noncommunicable diseases (NCDs). Current systems are insufficient for achieving blood pressure control among PWH. Further research and funding for efforts to address HIV and NCD care in Kenya are warranted.

摘要

目的

艾滋病毒感染者(PWH)面临心血管疾病风险增加,部分原因是高血压风险上升。本研究评估了肯尼亚艾滋病毒感染者随时间推移的高血压负担(即发病率和患病率)。

设计

纵向、开放队列研究。

方法

我们利用2004年至2023年的电子病历,估计了科普特希望中心大量肯尼亚艾滋病毒感染者样本中的高血压发病率和患病率。我们将新发高血压定义为基线后首次就诊时,每位患者收缩压至少140mmHg和/或舒张压至少90mmHg。

结果

我们的样本包括在肯尼亚科普特希望中心诊所寻求治疗的38709名艾滋病毒感染者(2004 - 2023年)。近40%的患者初诊时患有高血压。在最初血压正常的60%患者中,近40%在20年内患上了高血压。高血压的年患病率在8%至58%之间。与21世纪初和2010年代就诊的患者相比,2019年至2023年首次就诊的患者平均收缩压更高。

结论

我们的研究结果显示,在肯尼亚一个大型的基于信仰的卫生系统中,艾滋病毒感染者的高血压负担很高且呈上升趋势。这凸显了加强对同时感染艾滋病毒、高血压和其他非传染性疾病(NCDs)患者护理整合的必要性。目前的系统不足以实现艾滋病毒感染者的血压控制。有必要对肯尼亚应对艾滋病毒和非传染性疾病护理的努力进行进一步研究和提供资金。

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