创伤患者中酒精滥用的影响:范围综述方案。

The impact of alcohol misuse in trauma patients: A scoping review protocol.

作者信息

Garland Chantae, Abdulla Nhayan, Lee Donghyun, Spiwak Rae, Logsetty Sarvesh, Nantais Jordan

机构信息

Department of Surgery, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

Department of Surgery, McGill University, Montreal, Quebec, Canada.

出版信息

PLoS One. 2024 Oct 30;19(10):e0301241. doi: 10.1371/journal.pone.0301241. eCollection 2024.

Abstract

BACKGROUND

Alcohol use is a contributing factor in many cases of traumatic injury. There is conflicting evidence on the impact of alcohol use at the time of physical trauma on severity of injury and hospital course. Similarly, the significance of alcohol use disorder on outcomes in hospitalized trauma patients is unclear. This scoping review aims to provide a concise overview of the current literature surrounding peri-trauma alcohol use and alcohol use disorder on injury severity, in-hospital complications, patient outcomes, and long-term health impact of alcohol use in trauma. We will also explore the associated healthcare costs of this patient population.

METHODS

A systematic search of the following databases MEDLINE, EMBASE, and Cochrane Library will be completed to extract all studies that meet our inclusion criteria from January 2000 onwards. Case reports will be excluded. Two reviewers will screen all citations, abstracts, and full text articles. A third reviewer will act as tiebreaker at each stage of the screening process. A narrative synthesis without meta-analysis will be conducted and assessed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines.

DISCUSSION

This review will contribute to the literature by providing a concise overview of the current data on the impact of alcohol on outcomes following trauma. We will explore the overall themes in the literature, limitations, and future directions to focus forthcoming research in this patient population.

SCOPING REVIEW REGISTRATION

This project is registered via the Open Science Framework. The public registration is uniquely identified with the following DOI: https://doi.org/10.17605/OSF.IO/Z84WK.

SUPPORT

There were no funders or sponsors involved in the development of this protocol.

摘要

背景

酒精使用是许多创伤性损伤的一个促成因素。在身体受到创伤时的酒精使用对损伤严重程度和住院过程的影响方面存在相互矛盾的证据。同样,酒精使用障碍对住院创伤患者结局的意义也不清楚。本范围综述旨在提供一个简明概述,概述围创伤性酒精使用和酒精使用障碍对创伤后损伤严重程度、住院并发症、患者结局以及酒精使用对创伤后长期健康影响的当前文献。我们还将探讨这一患者群体相关的医疗保健费用。

方法

将对 MEDLINE、EMBASE 和 Cochrane Library 这三个数据库进行系统检索,以提取自 2000 年 1 月以来符合纳入标准的所有研究。将排除病例报告。两名审查员将筛选所有引文、摘要和全文文章。在筛选过程的每个阶段,第三名审查员将充当裁决人。将进行叙述性综合分析,不进行荟萃分析,并根据系统评价和荟萃分析扩展的首选报告项目(PRISMA-ScR)指南进行评估。

讨论

本综述将通过提供当前关于酒精对创伤后结局影响的数据的简明概述,为文献做出贡献。我们将探讨文献中的总体主题、局限性和未来方向,以聚焦该患者群体的未来研究。

范围综述注册

本项目通过开放科学框架进行注册。公共注册使用唯一的 DOI 进行识别:https://doi.org/10.17605/OSF.IO/Z84WK。

支持

在制定本方案时,没有资助者或赞助商参与。

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