Tajima Yuki, Komiyama Mayu, Mimura Naoya, Yamamoto Maika, Fukuie Marina, Suzuki Rina, Matsushima Shinya, Hirasawa Ai, Shibata Shigeki
Faculty of Health Sciences, Department of Physical Therapy, Kyorin University, Tokyo, Japan.
Japan Society for the Promotion of Science, Tokyo, Japan.
Clin Auton Res. 2025 Apr;35(2):231-241. doi: 10.1007/s10286-024-01077-6. Epub 2024 Oct 30.
Water intake is known to be effective in preventing orthostatic hypotension (OH). However, it is unknown whether water intake would be effective in acutely preventing exercise-induced OH.
Fourteen adults (men/women: 7/7, age: 20 ± 8 years) were recruited. Each subject underwent two protocols with and without 500 ml water intake using a randomized crossover design (Water vs. Control). Participants underwent 30 min of cycle ergometry at the 60-70% predicted VO max. OH and hemodynamics were assessed before and after exercise, and immediately (Water 1) and 20 min (Water 2) after the water intake. OH was evaluated with a 1-min standing test as the criteria for systolic blood pressure (SBP) < 90 mmHg. A cross-spectral analysis for RR and SBP variability was used to evaluate the cardiac autonomic activity and baroreflex sensitivity.
In both protocols, the incidence of OH increased after the exercise. The incidence of OH was lower in Water than in Control at Water 1 (OR: 0.093, 95% CI: 0.015-0.591). Heart rate was lower and SBP was higher in Water than in Control at Water 1 and 2 (P < 0.05). High-frequency power of RR variability and transfer function gains in Water were normalized and higher than in Control at Water 1 and 2 (P < 0.05). The ratio of low- to high-frequency power of RR variability in Water was normalized and lower in Water than in Control at Water 1 (P < 0.05).
Our findings indicate that water intake may prevent acute exercise-induced OH, accompanied by normalized cardiac autonomic activity and baroreflex sensitivity.
已知饮水对预防体位性低血压（OH）有效。然而，饮水是否能有效急性预防运动诱发的OH尚不清楚。
招募了14名成年人（男性/女性：7/7，年龄：20±8岁）。采用随机交叉设计，每位受试者进行了两次方案，一次饮水500ml，一次不饮水（饮水组与对照组）。参与者在预测最大摄氧量的60 - 70%下进行30分钟的蹬车运动。在运动前后以及饮水后即刻（饮水1）和20分钟（饮水2）评估OH和血流动力学。以1分钟站立试验作为收缩压（SBP）<90mmHg的标准来评估OH。采用RR和SBP变异性的交叉谱分析来评估心脏自主神经活动和压力反射敏感性。
在两个方案中，运动后OH的发生率均增加。在饮水1时，饮水组OH的发生率低于对照组（比值比：0.093，95%置信区间：0.015 - 0.591）。在饮水1和饮水2时，饮水组的心率低于对照组，SBP高于对照组（P<0.05）。饮水组RR变异性的高频功率和传递函数增益在饮水1和饮水2时恢复正常且高于对照组（P<0.05）。饮水组RR变异性的低频与高频功率之比在饮水1时恢复正常且低于对照组（P<0.05）。
我们的研究结果表明，饮水可能预防急性运动诱发的OH，并伴有心脏自主神经活动和压力反射敏感性的恢复正常。
