Department of Medicine, University of Florida, Gainesville, Florida, USA
Department of Medicine, University of Florida, Gainesville, Florida, USA.
BMJ Case Rep. 2024 Oct 30;17(10):e259847. doi: 10.1136/bcr-2024-259847.
Pulmonary hamartomas are abnormal growths of mature cell or tissue types, including cartilage, epithelium, fat or muscle. Although most cases are benign, asymptomatic and often incidentally discovered, these masses may provoke significant complications via predisposition to obstruction, ischaemia or infection. Pulmonary hamartomas located within the tracheal lumen are exceedingly rare clinical entities which produce symptoms of dyspnoea, cough, stridor, wheezing or angina. Significant clinical consequences include airway obstruction and cardiovascular collapse. Most cases of tracheal hamartoma are initially diagnosed as obstructive pulmonary disease. We present a structured case report of a tracheal hamartoma identified in a patient with recent coronary artery bypass grafting who was initially evaluated for persistent ischaemic pathology, resulting in delay of diagnosis. By review of limited literature of this disorder, we emphasise the need for clinicians to be aware of this indolent and rare entity.
肺错构瘤是成熟细胞或组织类型的异常生长,包括软骨、上皮、脂肪或肌肉。尽管大多数病例是良性的、无症状的,且常为偶然发现,但这些肿块可能因易发生阻塞、缺血或感染而引起严重并发症。位于气管腔内的肺错构瘤是非常罕见的临床实体,可引起呼吸困难、咳嗽、喘鸣、哮鸣或心绞痛等症状。严重的临床后果包括气道阻塞和心血管衰竭。大多数气管错构瘤病例最初被诊断为阻塞性肺病。我们报告了 1 例接受过冠状动脉旁路移植术的患者的气管错构瘤病例,该患者最初因持续性缺血性病变而被评估,导致诊断延迟。通过对该疾病有限的文献回顾,我们强调临床医生需要意识到这种惰性和罕见的实体。