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改良咽鼓管咽肌肌黏膜瓣:一种用于颅底重建的新技术。

Modified salpingopharyngeus myomucosal flap: a novel technique for skull base reconstruction.

作者信息

Fadel Michael, Alsavaf Mohammad Bilal, Salem Eman H, Gun Ramazan, Prevedello Daniel M, Vankoevering Kyle K, Hardesty Douglas A, Kelly Kathleen, Carrau Ricardo L

机构信息

Department of Otolaryngology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center at The Ohio State University, Columbus, OH, USA.

出版信息

Eur Arch Otorhinolaryngol. 2025 Jan;282(1):257-263. doi: 10.1007/s00405-024-09026-9. Epub 2024 Oct 31.

Abstract

PURPOSE

Advancements in endoscopic skull base surgery have enabled complex tumor resections, necessitating a variety of reliable reconstructive techniques to repair resultant defects. Vascularized flaps represent optimal options, but frequently used local pedicled intranasal flaps may be unavailable due to tumor invasion or prior surgery. This study applies a modification to the previously described salpingopharyngeus myomucosal flap (Dicle flap) with potential for its use in extensive endoscopic skull base surgery defect's repair.

METHODS

Cadaveric dissections (n = 5) were performed utilizing endoscopic visualization to access the skull base via endonasal and transoral routes. A superiorly based posterior pharyngeal myomucosal flap along the salpingopharyngeus muscle was elevated off the superior pharyngeal constrictors, preserving their vascular pedicles. This combined flap could be 180 degrees transposed to reconstruct clival defects up to the sella turcica.

RESULTS

The modified salpingopharyngeus myomucosal flap (Modified Dicle flap) provided approximately 40 cm of robust vascularized tissue based on the ascending pharyngeal artery and random posterior pharyngeal vessels. It was sufficiently mobilized to cover extensive skull base defects in the craniocervical junction, sella turcica, and protecting the exposed internal carotid artery segments.

CONCLUSION

The modified Dicle flap offers a viable reconstructive option for extensive endoscopic endonasal skull base defects when commonly utilized vascularized flaps are unavailable. Further research on clinical cases is warranted to investigate postoperative function and refine techniques to minimize donor site morbidity.

LEVEL OF EVIDENCE

Not applicable.

摘要

目的

内镜颅底手术的进展使得复杂肿瘤切除术成为可能,这就需要多种可靠的重建技术来修复由此产生的缺损。带血管蒂皮瓣是最佳选择,但由于肿瘤侵犯或既往手术,常用的局部带蒂鼻内皮瓣可能无法使用。本研究对先前描述的咽鼓管咽肌肌黏膜瓣(迪克尔瓣)进行了改良,使其有可能用于广泛的内镜颅底手术缺损修复。

方法

利用内镜可视化技术,通过鼻内和经口途径进行尸体解剖(n = 5)。沿着咽鼓管咽肌掀起一块以咽鼓管咽肌为基底的后咽肌黏膜瓣,使其与咽上缩肌分离,保留其血管蒂。该联合皮瓣可进行180度移位,以重建直至蝶鞍的斜坡缺损。

结果

改良后的咽鼓管咽肌肌黏膜瓣(改良迪克尔瓣)基于咽升动脉和随机的后咽血管提供了约40厘米的强健带血管蒂组织。它能够充分游离,以覆盖颅颈交界、蝶鞍处的广泛颅底缺损,并保护暴露的颈内动脉段。

结论

当常用的带血管蒂皮瓣无法使用时,改良迪克尔瓣为广泛的内镜鼻内颅底缺损提供了一种可行的重建选择。有必要对临床病例进行进一步研究,以调查术后功能并改进技术,将供区并发症降至最低。

证据水平

不适用。

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