母亲在分娩期给药后脐带血中庆大霉素的浓度。
Umbilical cord blood gentamicin concentrations following maternally-administered intrapartum exposures.
作者信息
Coggins Sarah A, Wade Kelly C, Watt Kevin M, Downes Kevin J, Puopolo Karen M
机构信息
Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Department of Pediatrics, University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Pediatr Res. 2024 Oct 30. doi: 10.1038/s41390-024-03698-z.
PMID:39478198
Abstract
We identified cord blood gentamicin concentrations that were higher than anticipated, and above clinical targets for immediate gentamicin re-dosing after birth. Incorporation of gentamicin levels at birth may aid in optimizing postnatal gentamicin dosing among infants exposed to intrapartum gentamicin.
摘要
我们发现脐带血中庆大霉素浓度高于预期，且高于出生后立即重新注射庆大霉素的临床目标值。纳入出生时的庆大霉素水平可能有助于优化暴露于产时庆大霉素的婴儿出生后的庆大霉素给药方案。
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