Liu Qinqin, Chen Ping, Xin Li, Zhang Jiahao, Jiang Meijie
Department of Hematology, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Department of Gastroenterology, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Front Med (Lausanne). 2024 Oct 16;11:1435239. doi: 10.3389/fmed.2024.1435239. eCollection 2024.
Mucormycosis is an aggressive fungal disease. Gastrointestinal mucormycosis is rare, but its clinical symptoms lack specificity and mortality is high. Here, we report a case of intestinal mucormycosis caused by in a 65-year-old woman with diabetes mellitus. The patient exhibited extensive mucosal tissue damage in the colon, with broad, undivided filamentous fungal hyphae present in the intestinal tissue. Therefore, the patient was suspected to have a filamentous fungal infection. Colonic tissue samples were obtained for fungal culture, and the fungus was identified as based on morphology and DNA sequencing. This case highlights the importance of pathologists and microbiologists in identifying pathogenic fungi and the significance of screening for mucormycosis in high-risk patient populations.
毛霉病是一种侵袭性真菌病。胃肠道毛霉病较为罕见，但其临床症状缺乏特异性且死亡率高。在此，我们报告一例由 引起的肠道毛霉病，患者为一名65岁的糖尿病女性。该患者结肠出现广泛的黏膜组织损伤，肠道组织中存在粗大、无分隔的丝状真菌菌丝。因此，怀疑该患者有丝状真菌感染。获取结肠组织样本进行真菌培养，并根据形态学和DNA测序将该真菌鉴定为 。本病例凸显了病理学家和微生物学家在鉴定致病真菌方面的重要性以及在高危患者群体中筛查毛霉病的意义。
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