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1例腹膜透析患者的无糖棒状杆菌腹膜炎:病例报告及文献复习

Corynebacterium amycolatum peritonitis in a patient undergoing peritoneal dialysis: case report and literature review.

作者信息

Adil Fatima Zahra, Aragon Imane, Benaissa Elmostafa, Ben Lahlou Yassine, Bssaibis Fatna, Maleb Adil, Chadli Mariama, Elouennass Mostafa

机构信息

Bacteriology Department, Mohammed V Military Teaching Hospital, Rabat, Morocco.

Nephrology Department, Mohammed V Military Teaching Hospital, Rabat, Morocco.

出版信息

Access Microbiol. 2024 Oct 30;6(10). doi: 10.1099/acmi.0.000880.v3. eCollection 2024.

Abstract

Peritoneal dialysis is a blood purification technique used in cases of end-stage chronic kidney failure, based on the filtering capabilities of the peritoneum. Infections, often caused by poor asepsis during catheter manipulation, are generally attributed to and , usually considered non-pathogenic, is rarely involved in these infections. We present a case of peritonitis due to in a patient undergoing peritoneal dialysis. The diagnosis was made based on cytobacteriological examination of the dialysate fluid, which on two occasions showed high levels of white blood cells with a predominance of neutrophilic polymorphonuclear and a monomorphic appearance of colonies on agar medium, whose identification by biochemical tests and antibiotic sensitivity study confirmed the presence of . The patient was successfully treated with vancomycin, resulting in symptom resolution and sterilization of the dialysate fluid. Although rare, the involvement of species underscores the importance of confirming its pathogenicity. Further studies are needed to better understand the epidemiology of these infections and guide future treatments. This case also highlights the need for a rigorous approach to confirming the pathogenicity of despite its traditional classification as a contaminant.

摘要

腹膜透析是一种用于终末期慢性肾衰竭病例的血液净化技术,基于腹膜的过滤能力。感染通常由导管操作过程中无菌操作不当引起,一般归因于[具体细菌A]和[具体细菌B],[具体细菌C]通常被认为是非致病性的,很少参与这些感染。我们报告一例正在接受腹膜透析的患者因[具体细菌C]引起腹膜炎的病例。诊断基于透析液的细胞细菌学检查,该检查两次显示白细胞水平高,以嗜中性多形核细胞为主,在琼脂培养基上菌落呈单形外观,通过生化试验和抗生素敏感性研究对其进行鉴定,证实存在[具体细菌C]。患者用万古霉素成功治疗,症状缓解,透析液除菌。尽管[具体细菌C]感染罕见,但它的累及强调了确认其致病性的重要性。需要进一步研究以更好地了解这些感染的流行病学并指导未来治疗。该病例还强调,尽管[具体细菌C]传统上被归类为污染物,但仍需要采取严谨方法来确认其致病性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa6/11524318/e646a9ff577b/acmi-6-00880-g001.jpg

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