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食用猕猴桃对成年人人体测量和心脏代谢指标的影响:一项系统评价和荟萃分析。

The effects of kiwifruit consumption on anthropometric and cardiometabolic indices in adults: A systematic review and meta-analysis.

作者信息

Pam Pedram, Goudarzi Mohammad Ali, Ghotboddin Mohammadi Shirin, Asbaghi Omid, Aghakhani Ladan, Clark Cain C T, Hashempur Mohammad Hashem, Haghighat Neda

机构信息

Student Research Committee, Department of Clinical Nutrition Tabriz University of Medical Sciences Tabriz Iran.

Department of Clinical Nutrition Tabriz University of Medical Sciences Tabriz Iran.

出版信息

Food Sci Nutr. 2024 Aug 9;12(10):7017-7032. doi: 10.1002/fsn3.4385. eCollection 2024 Oct.

Abstract

The current systematic review and meta-analysis was conducted to evaluate the effects of kiwifruit intake on anthropometric indices and key cardiometabolic parameters. Related articles were found by searching PubMed, ISI Web of Science, and Scopus to detect relevant Randomized Clinical Trials (RCTs) and novel systematic reviews relating to kiwi consumption in adults, up to August 2023. The weighted mean difference (WMD) and 95% confidence intervals (CIs) were calculated using a random-effects model. Heterogeneity, sensitivity analysis, and publication bias were assessed and reported using standard methods. Six RCTs were included in the meta-analysis. Analyzing overall effect sizes demonstrated a significant reduction in low-density lipoprotein cholesterol (LDL) levels (WMD: -9.30 mg/dL; 95% CI: -17.56 to -1.04,  = .027), whereas no significant alterations of triglycerides (TG) (WMD: -12.91 mg/dL; 95% CI: -28.17 to 2.34,  = .097), total cholesterol (TC) (WMD: -7.66 mg/dL; 95% CI: -17.85 to 2.52,  = .141), high-density lipoprotein cholesterol (HDL) (WMD: 2.87 mg/dL; 95% CI: -0.36 to 6.11,  = .141), fasting blood glucose (FBG) (WMD: 1.06 mg/dL; 95% CI: -1.43 to 3.56,  = .404), C-reactive protein (CRP) (WMD: 0.15 mg/dL; 95% CI: -0.40, 0.70,  = .0598), body weight (BW) (WMD: 0.85 kg; 95% CI: -1.34 to 3.04,  = .448), body mass index (BMI) (WMD: 0.04 kg/m; 95% CI: -0.75 to 0.83,  = .920), and waist circumference (WC) (WMD: 0.18 cm; 95% CI: -1.81 to 2.19,  = .855) were found. Our findings suggest that consuming kiwifruit does not have a significant impact on anthropometric indices and cardiometabolic factors, except for LDL-C levels.

摘要

本系统评价和荟萃分析旨在评估摄入猕猴桃对人体测量指标和关键心脏代谢参数的影响。通过检索PubMed、ISI科学网和Scopus查找相关文章,以检测截至2023年8月有关成人食用猕猴桃的随机临床试验(RCT)和新的系统评价。使用随机效应模型计算加权平均差(WMD)和95%置信区间(CI)。采用标准方法评估并报告异质性、敏感性分析和发表偏倚。荟萃分析纳入了6项RCT。分析总体效应量显示,低密度脂蛋白胆固醇(LDL)水平显著降低(WMD:-9.30mg/dL;95%CI:-17.56至-1.04,P=0.027),而甘油三酯(TG)(WMD:-12.91mg/dL;95%CI:-28.17至2.34,P=0.097)、总胆固醇(TC)(WMD:-7.66mg/dL;95%CI:-17.85至2.52,P=0.141)、高密度脂蛋白胆固醇(HDL)(WMD:2.87mg/dL;95%CI:-0.36至6.11,P=0.141)、空腹血糖(FBG)(WMD:1.06mg/dL;95%CI:-1.43至3.56,P=0.404)、C反应蛋白(CRP)(WMD:0.15mg/dL;95%CI:-0.40,0.70,P=0.0598)、体重(BW)(WMD:0.85kg;95%CI:-1.34至3.04,P=0.448)、体重指数(BMI)(WMD:0.04kg/m;95%CI:-0.75至0.83,P=0.920)和腰围(WC)(WMD:0.18cm;95%CI:-1.81至2.19,P=0.855)均无显著变化。我们的研究结果表明,除LDL-C水平外,食用猕猴桃对人体测量指标和心脏代谢因素没有显著影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e69/11521643/10ec5e1d9f89/FSN3-12-7017-g004.jpg

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