Teano Valerie J, Weikel Blair W, Hwang Sunah S, Wymore Erica M, Blackwell Sarah, Bourque Stephanie L
Department of Pediatrics, Graduate Medical Education, University of Colorado School of Medicine, 13121 E. 17th Ave., Aurora, CO, 80045, USA.
Department of Pediatrics, Section of Neonatology, University of Colorado School of Medicine, Aurora, CO, USA.
Arch Womens Ment Health. 2025 Jun;28(3):603-611. doi: 10.1007/s00737-024-01515-4. Epub 2024 Oct 31.
To evaluate the prevalence and predictors of cannabis use and reasons for use during and/or after pregnancy among Colorado birthing individuals. To determine the independent association of self-reported depression during pregnancy and cannabis used.
Data from Health eMoms, a statewide perinatal longitudinal electronic surveillance system were analyzed. Perinatal cannabis use was defined as any use during and/or after pregnancy. Bivariate associations of birthing individual and infant characteristics with use were estimated using chi-square tests. Multivariable logistic regression was used to assess the independent relationship between depression and reported cannabis use versus no reported cannabis use.
A weighted sample of 117,812 birthing individuals was analyzed from survey responses between 2018-2021. Among the 15,585 (13.3%) who reported perinatal cannabis use, 35.5% reported use during pregnancy and 87.3% reported post-partum use. Individuals with depression during pregnancy had 2.2 times higher adjusted odds (95% CI: 1.5. 3.3) of any perinatal cannabis use compared to those without depression. Among those who had any perinatal cannabis use, reported use for medical reasons was 92% during pregnancy, while 43% cited this as the reason for use 12-14 months post-partum.
Self-reported cannabis use during the perinatal period in a state with legalized recreational use was over 1 in 10. Use varied significantly by demographics and social factors with inconsistent perinatal guidance provided by healthcare professionals. Depression during pregnancy was significantly associated with use, illustrating the need for comprehensive mental health screening and therapeutic evidence-based interventions to support these individuals.
评估科罗拉多州分娩人群孕期及产后大麻使用的患病率、预测因素及使用原因。确定孕期自我报告的抑郁症与大麻使用之间的独立关联。
分析了来自全州围产期纵向电子监测系统Health eMoms的数据。围产期大麻使用定义为孕期及产后的任何使用情况。使用卡方检验估计分娩人群和婴儿特征与大麻使用之间的双变量关联。多变量逻辑回归用于评估抑郁症与报告的大麻使用和未报告的大麻使用之间的独立关系。
对2018 - 2021年调查回复中的117,812名分娩人群加权样本进行了分析。在报告围产期大麻使用的15,585人（13.3%）中，35.5%报告在孕期使用，87.3%报告在产后使用。孕期患抑郁症的人群围产期任何大麻使用的调整后优势比是未患抑郁症人群的2.2倍（95%置信区间：1.5，3.3）。在有围产期大麻使用的人群中，报告孕期因医疗原因使用的占92%，而产后12 - 14个月将此作为使用原因的占43%。
在娱乐大麻使用合法化的州，自我报告的围产期大麻使用率超过十分之一。使用率因人口统计学和社会因素有显著差异，医疗保健专业人员提供的围产期指导不一致。孕期抑郁症与大麻使用显著相关，这表明需要进行全面的心理健康筛查和基于治疗证据的干预措施来支持这些人群。
