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患有阿片类物质使用障碍的退伍军人在2019冠状病毒病期间的急诊科就诊、住院治疗以及非致命和致命药物过量情况

Emergency Department Visits, Inpatient Hospitalizations, and Nonfatal and Fatal Drug Overdoses During COVID-19 Among Veterans With Opioid Use Disorder.

作者信息

Livingston Nicholas A, Mandavia Amar D, Banducci Anne N, Loeffel Lauren B, Sistad Hall Rebecca, Maloney Molly, Roth Clara E, Fonda Jennifer R, Davenport Michael, Meng Frank, Hyde Justeen, Stein Michael

机构信息

National Center for PTSD, Behavioral Sciences Division, Veterans Affairs (VA) Boston Healthcare System, Boston, Massachusetts.

Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts.

出版信息

J Stud Alcohol Drugs. 2025 Jul;86(4):582-589. doi: 10.15288/jsad.24-00184. Epub 2024 Oct 31.

Abstract

OBJECTIVE

The COVID-19 pandemic had dramatic adverse impacts on people with opioid use disorder (OUD), as evidenced by significant disruptions to care and unprecedented increases in drug overdoses. In this study, we evaluated the impacts of COVID-19 on the use of emergency and inpatient care and fatal and nonfatal overdoses among veterans with OUD.

METHOD

We used Veterans Health Administration (VHA) electronic medical record and mortality data to compare emergency department visits, inpatient hospitalizations, and fatal and nonfatal overdoses between a pandemic-exposed cohort of veterans with OUD observed both before and after the onset of the pandemic ( = 53,803; observed January 2019 to March 2021) to a matched prepandemic control group ( = 53,803; observed October 2017 to December 2019).

RESULTS

Compared with pre-pandemic trends, there were significant decreases in the odds of emergency department and inpatient admissions and the total number of emergency department and inpatient admissions during COVID-19. There was a significant decrease in the odds of having a recorded nonfatal overdose. The odds of overdose death increased during the pandemic compared with pre-pandemic trends.

CONCLUSIONS

We observed significant decreases in the use of emergency department and inpatient care services and fewer nonfatal overdoses after the pandemic's onset. Health care disruptions limiting access to emergency and inpatient care could account for the lower number of recorded nonfatal overdoses, potentially reflecting an underestimate of risk. In contrast, fatal overdoses increased during the pandemic compared with pre-pandemic trends. Lower use of emergency and inpatient care and higher rates of fatal overdoses during the pandemic suggest an exacerbation of unmet treatment needs after the pandemic's onset.

摘要

目的

2019年冠状病毒病(COVID-19)大流行对患有阿片类物质使用障碍(OUD)的人群产生了巨大的不利影响,护理的严重中断和药物过量服用前所未有的增加证明了这一点。在本研究中,我们评估了COVID-19对患有OUD的退伍军人使用急诊和住院护理以及致命和非致命药物过量的影响。

方法

我们使用退伍军人健康管理局(VHA)的电子病历和死亡率数据,比较了在大流行爆发之前和之后观察到的患有OUD的退伍军人暴露于大流行的队列(n = 53,803;观察时间为2019年1月至2021年3月)与匹配的大流行前对照组(n = 53,803;观察时间为2017年10月至2019年12月)之间的急诊就诊、住院治疗以及致命和非致命药物过量情况。

结果

与大流行前的趋势相比,在COVID-19期间,急诊和住院入院的几率以及急诊和住院入院的总数均显著下降。有记录的非致命药物过量的几率显著下降。与大流行前的趋势相比,大流行期间药物过量死亡的几率有所增加。

结论

我们观察到在大流行开始后,急诊和住院护理服务的使用显著减少,非致命药物过量的情况也减少。医疗保健中断限制了获得急诊和住院护理的机会,这可能是记录的非致命药物过量数量较低的原因,这可能反映了风险被低估。相比之下,与大流行前的趋势相比,大流行期间致命药物过量有所增加。大流行期间急诊和住院护理的使用减少以及致命药物过量率升高表明,大流行开始后未满足的治疗需求加剧。

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