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一名老年男性患者上颌颊腭侧牙龈发生的外周骨化性纤维瘤:一例罕见病例报告

Peripheral ossifying fibroma arising from the maxillary bucco-palatal gingiva in an elderly male patient: a rare case report.

作者信息

An Seo-Yeong, Kim Chan Min, Sung Chi Heon, Kim Chul-Hwan

机构信息

Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University, Cheonan, Korea.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2024 Oct 31;50(5):292-296. doi: 10.5125/jkaoms.2024.50.5.292.

Abstract

Peripheral ossifying fibroma (POF) is a benign tumor characterized by dystrophic calcification or ossification within the gingiva, primarily affecting the anterior maxilla of females and young adults. Its pathogenesis is unclear but linked to local irritants such as trauma, biofilm, dental calculus, and poorly fitting prostheses. In this study, a 63-year-old male presented at Dankook University Dental Hospital with a large nodular lesion on the left maxillary bucco-palatal gingiva. Preoperative imaging, including panoramic radiography and cone-beam computed tomography, was performed. Surgical excision and histological examination confirmed POF with specific morphological characteristics, including mineralized tissue with varied deposition patterns, mature and immature bone, cementum-like tissue, and dystrophic calcification. In conclusion, POF is a rare oral tumor, more common in younger females, typically presenting asymptomatically on the anterior maxilla. Histopathological analysis is crucial for diagnosis. Standard treatment involves conservative local resection, but recurrence rates range from 8% to 20%, necessitating continuous follow-up. This report aims to enhance understanding of POF by presenting a rare case of a large POF in the maxillary posterior bucco-palatal gingiva of an elderly male.

摘要

外周骨化性纤维瘤(POF)是一种良性肿瘤,其特征是牙龈内出现营养不良性钙化或骨化,主要影响女性和年轻人的上颌前部。其发病机制尚不清楚,但与创伤、生物膜、牙结石和不合适的假牙等局部刺激因素有关。在本研究中,一名63岁男性因左上颌颊腭侧牙龈出现一个大的结节性病变就诊于檀国大学牙医院。进行了术前影像学检查,包括全景X线摄影和锥形束计算机断层扫描。手术切除和组织学检查证实为具有特定形态特征的外周骨化性纤维瘤,包括具有不同沉积模式的矿化组织、成熟和不成熟的骨、牙骨质样组织以及营养不良性钙化。总之,外周骨化性纤维瘤是一种罕见的口腔肿瘤,在年轻女性中更为常见,通常在上颌前部无症状出现。组织病理学分析对诊断至关重要。标准治疗包括保守的局部切除,但复发率在8%至20%之间,需要持续随访。本报告旨在通过呈现一例老年男性上颌后颊腭侧牙龈出现的大型外周骨化性纤维瘤的罕见病例,提高对该疾病的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e62e/11535121/e1cc8aed6082/jkaoms-50-5-292-f1.jpg

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