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使用支架置入术成功治疗对多种疗法难治的血管痉挛性心绞痛:一例报告。

Successful treatment of vasospastic angina refractory to various therapies using stenting: A case report.

作者信息

Ono Morio, Okabe Toshitaka, Isomura Naoei, Ochiai Masahiko

机构信息

Division of Cardiology, Showa University Northern Yokohama Hospital, Tsuzuki, Yokohama, Japan.

出版信息

J Cardiol Cases. 2024 Jun 15;30(3):97-100. doi: 10.1016/j.jccase.2024.05.010. eCollection 2024 Sep.

DOI:10.1016/j.jccase.2024.05.010
PMID:39483406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11523208/
Abstract

UNLABELLED

We encountered a case of coronary angina refractory to multiple medications, including a calcium channel blocker, nitroglycerin, fasudil (a Rho kinase inhibitor), left stellate ganglion block, thoracic sympathetic ganglion blockade, steroids, and denopamine. During the course of treatment, ventricular tachycardia (VT) occurred due to ST-segment elevation, and an implantable cardioverter-defibrillator was implanted; however, the patient had recurrent VT. A 12‑lead electrocardiogram showed ST elevation localized to leads II, III, and a Vf, and stenting was performed in all main trunks of the right coronary artery. After stenting, the daily angina attacks stopped, VT disappeared, and the chronic phase was controlled with her existing drug therapy, although she had mild chest pain attacks. There is limited evidence regarding the treatment of refractory angina pectoris. In this case, a patient with coronary angina pectoris refractory to various therapies underwent stenting, and the potentially fatal arrhythmia disappeared.

LEARNING OBJECTIVE

Management of refractory coronary angina pectoris poses a challenge. Despite attempting conventional therapies, our initial efforts were met with unsuccessful outcomes. Finally, we succeeded in treating the patient with stenting. This case report underscores the challenge of managing refractory coronary angina and explores diverse therapeutic approaches, including conventional medications, sympathetic nerve interventions, and stent placement.

摘要

未标注

我们遇到了一例对多种药物难治的冠状动脉性心绞痛病例,这些药物包括钙通道阻滞剂、硝酸甘油、法舒地尔(一种Rho激酶抑制剂)、左侧星状神经节阻滞、胸交感神经节阻滞、类固醇和多巴胺丁胺。在治疗过程中,由于ST段抬高出现了室性心动过速(VT),并植入了植入式心脏复律除颤器;然而,患者仍反复出现室性心动过速。一份12导联心电图显示ST段抬高局限于II、III和aVF导联,遂对右冠状动脉的所有主要分支进行了支架置入术。支架置入术后,每日心绞痛发作停止,室性心动过速消失,尽管患者仍有轻度胸痛发作,但在慢性期通过现有的药物治疗得到了控制。关于难治性心绞痛的治疗证据有限。在本病例中,一名对各种治疗均难治的冠状动脉性心绞痛患者接受了支架置入术,潜在的致命性心律失常消失。

学习目标

难治性冠状动脉性心绞痛的管理具有挑战性。尽管尝试了传统疗法,但我们最初的努力并未取得成功。最终,我们成功地通过支架置入术治疗了该患者。本病例报告强调了管理难治性冠状动脉性心绞痛的挑战,并探讨了包括传统药物、交感神经干预和支架置入在内的多种治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/840fd6b85da8/mmc2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/790db59eb02d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/b9b14aaf1dd2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/efcc6e0a00e6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/adb6910f0640/mmc1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/840fd6b85da8/mmc2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/790db59eb02d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/b9b14aaf1dd2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/efcc6e0a00e6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/adb6910f0640/mmc1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d79b/11523208/840fd6b85da8/mmc2.jpg

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本文引用的文献

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Optimal Medications and Appropriate Implantable Cardioverter-defibrillator Shocks in Aborted Sudden Cardiac Death Due to Coronary Spasm.冠状动脉痉挛所致心脏性猝死未遂的最佳药物治疗及适当的植入式心律转复除颤器电击治疗
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Endoscopic thoracic sympathectomy as a novel strategy for vasospastic angina refractory to medical treatments.胸腔镜胸交感神经切断术作为一种治疗药物难治性血管痉挛性心绞痛的新策略。
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