秋水仙碱过量：静脉-动脉体外膜肺氧合及微轴流泵支持面临的挑战
Colchicine Overdose: Challenges With Venoarterial Extracorporeal Membrane Oxygenation and Microaxial Flow Pump Support.
作者信息
Golob Stephanie, Zhang Robert S, Medamana John L, Pires Kyle D, Cruz Jennifer, Grossman Jeremy, Biary Rana, DiVita Michael, Yuriditsky Eugene
机构信息
Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA.
Division of Medical Toxicology, Department of Emergency Medicine, NYU Grossman School of Medicine, New York, New York, USA.
出版信息
JACC Case Rep. 2024 Oct 2;29(19):102580. doi: 10.1016/j.jaccas.2024.102580.
Colchicine has an expanding role in cardiovascular disease treatment. Colchicine overdose is a toxicologic emergency. Direct cellular toxicity interferes with myocardial contractility, leading to cardiovascular collapse. We present a case of a patient with a colchicine overdose supported with venoarterial extracorporeal membrane oxygenation, highlighting the challenges and limitations.
秋水仙碱在心血管疾病治疗中的作用正在不断扩大。秋水仙碱过量是一种毒理学急症。直接的细胞毒性会干扰心肌收缩力，导致心血管衰竭。我们报告一例接受静脉-动脉体外膜肺氧合支持的秋水仙碱过量患者病例，突出了其中的挑战和局限性。
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