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高危人群的宫颈癌筛查:基层医疗中的临床挑战。

Cervical cancer screening in high-risk patients: Clinical challenges in primary care.

作者信息

Gold Rebecca S, Williams Meagan, Wainstein Heather M

机构信息

Acting Instructor, Provisional Chief, Department of Medicine, University of Washington School of Medicine, Seattle, WA

Veterans Administration Puget Sound Healthcare System, Seattle, WA

出版信息

Cleve Clin J Med. 2024 Nov 1;91(11):693-703. doi: 10.3949/ccjm.91a.24023.

Abstract

The risk of developing cervical cancer is not equal across populations-individual health history, economic, political, and societal factors influence cervical cancer risk. Certain health conditions, including human immunodeficiency virus (HIV) infection, immunosuppression, and history of high-grade cervical dysplasia, are associated with higher cervical cancer risk and warrant distinct screening, surveillance, and management guidelines. It is imperative for clinicians to recognize high-risk groups and apply appropriate corresponding guidelines. However, this can be difficult in practice, as recommendations regularly evolve. This review offers up-to-date guidance in a case-based format on cervical cancer screening, surveillance, and management for high-risk patients.

摘要

宫颈癌的发病风险在不同人群中并不均等——个体的健康史、经济、政治和社会因素均会影响宫颈癌的发病风险。某些健康状况,包括人类免疫缺陷病毒(HIV)感染、免疫抑制和高级别宫颈发育不良病史,与较高的宫颈癌发病风险相关,需要有明确的筛查、监测和管理指南。临床医生必须识别高危人群并应用相应的指南,但这在实践中可能具有挑战性,因为推荐意见在不断演变。本综述以病例为基础的形式就高危患者的宫颈癌筛查、监测和管理提供了最新的指导。

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