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本文引用的文献

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Association of in utero HIV exposure with child brain structure and language development: a South African birth cohort study.宫内 HIV 暴露与儿童大脑结构和语言发育的关系:南非出生队列研究。
BMC Med. 2024 Mar 22;22(1):129. doi: 10.1186/s12916-024-03282-6.
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Comparative risk of adverse perinatal outcomes associated with classes of antiretroviral therapy in pregnant women living with HIV: systematic review and meta-analysis.感染HIV的孕妇中不同类别抗逆转录病毒疗法相关围产期不良结局的比较风险:系统评价和荟萃分析
Front Med (Lausanne). 2024 Feb 27;11:1323813. doi: 10.3389/fmed.2024.1323813. eCollection 2024.
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Estimating the impact of alternative programmatic cotrimoxazole strategies on mortality among children born to mothers with HIV: A modelling study.评估不同方案的复方新诺明策略对 HIV 感染母亲所生儿童死亡率的影响:建模研究。
PLoS Med. 2024 Feb 20;21(2):e1004334. doi: 10.1371/journal.pmed.1004334. eCollection 2024 Feb.
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Risk and rates of hospitalisation in young children: A prospective study of a South African birth cohort.幼儿住院风险与住院率:一项南非出生队列的前瞻性研究。
PLOS Glob Public Health. 2024 Jan 17;4(1):e0002754. doi: 10.1371/journal.pgph.0002754. eCollection 2024.
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Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy.在普遍应用抗逆转录病毒疗法的背景下,与宫内 HIV/抗逆转录病毒治疗暴露相比,产妇母乳喂养和教育对婴儿的生长发育影响更大。
AIDS. 2024 Mar 15;38(4):537-546. doi: 10.1097/QAD.0000000000003785. Epub 2023 Nov 14.
6
Lower academic performance among children with perinatal HIV exposure in Botswana.博茨瓦纳围产期 HIV 暴露儿童的学业表现较差。
J Int AIDS Soc. 2023 Oct;26 Suppl 4(Suppl 4):e26165. doi: 10.1002/jia2.26165.
7
Children of a syndemic: co-occurring and mutually reinforcing adverse child health exposures in a prospective cohort of HIV-affected mother-infant dyads in Cape Town, South Africa.综合征儿童:南非开普敦受艾滋病毒影响母婴二人组前瞻性队列中同时发生和相互加强的不利儿童健康暴露。
J Int AIDS Soc. 2023 Oct;26 Suppl 4(Suppl 4):e26152. doi: 10.1002/jia2.26152.
8
Maternal and birth outcomes in pregnant people with and without HIV in the Western Cape, South Africa.南非西开普省有和无 HIV 的孕妇的母婴结局。
AIDS. 2024 Jan 1;38(1):59-67. doi: 10.1097/QAD.0000000000003728. Epub 2023 Nov 22.
9
Dolutegravir and pregnancy outcomes including neural tube defects in the USA during 2008-20: a national cohort study.2008-20 年美国多替拉韦与妊娠结局(包括神经管缺陷):一项全国队列研究。
Lancet HIV. 2023 Sep;10(9):e588-e596. doi: 10.1016/S2352-3018(23)00108-X. Epub 2023 Jul 25.
10
Co-trimoxazole prophylaxis for children who are HIV-exposed and uninfected: a systematic review.HIV 暴露但未感染儿童的复方磺胺甲噁唑预防:系统评价。
J Int AIDS Soc. 2023 Jun;26(6):e26079. doi: 10.1002/jia2.26079.

围产期暴露于人类免疫缺陷病毒的儿童的护理。

Care of the Child Perinatally Exposed to Human Immunodeficiency Virus.

机构信息

Department of Paediatrics and Child Health and Neuroscience Institute, University of Cape Town, Cape Town, South Africa.

Department of Paediatrics, AIC Kijabe Hospital, Kiambu, Kenya.

出版信息

Clin Perinatol. 2024 Dec;51(4):881-894. doi: 10.1016/j.clp.2024.08.011.

DOI:10.1016/j.clp.2024.08.011
PMID:39487026
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11781781/
Abstract

Substantial progress in preventing vertical human immunodeficiency virus (HIV) transmission has led to a dramatic decline in new pediatric HIV infections. Alongside this success, a growing population of children who are HIV-exposed but uninfected face unique health challenges due to a variety of risk factors. Recommendations for healthcare providers caring for this population include optimizing and integrating general and HIV-related care for both mother and child through comprehensive care packages. Further research and multidisciplinary approaches are needed to address the long-term health implications for this vulnerable population.

摘要

在预防垂直传播人类免疫缺陷病毒 (HIV) 方面取得了重大进展,导致新感染儿童 HIV 的人数大幅下降。随着这一成功,越来越多的 HIV 暴露但未感染的儿童由于各种风险因素而面临独特的健康挑战。为照顾这一人群的医疗保健提供者提出的建议包括通过综合护理包优化和整合母婴的一般护理和 HIV 相关护理。需要进一步的研究和多学科方法来解决这一弱势群体的长期健康影响。