文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

Anti-tau antibody stumbles in phase II Alzheimer trial.

作者信息

Mullard Asher

出版信息

Nat Rev Drug Discov. 2024 Dec;23(12):883. doi: 10.1038/d41573-024-00180-7.


DOI:10.1038/d41573-024-00180-7
PMID:39487218
Abstract
摘要

相似文献

[1]
Anti-tau antibody stumbles in phase II Alzheimer trial.

Nat Rev Drug Discov. 2024-12

[2]
Relating minimum toe clearance to prospective, self-reported, trip-related stumbles in the community.

Prosthet Orthot Int. 2017-8

[3]
Phase 1 Studies of the Anti-Tau Monoclonal Antibody JNJ-63733657 in Healthy Participants and Participants with Alzheimer's Disease.

J Prev Alzheimers Dis. 2024

[4]
Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial.

JAMA. 2023-8-8

[5]
Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease.

Arch Neurol. 2012-8

[6]
Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.

J Chromatogr A. 2021-8-16

[7]
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Proc Natl Acad Sci U S A. 1986-7

[8]
Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau.

J Neuropathol Exp Neurol. 2021-6-4

[9]
Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.

Proc Natl Acad Sci U S A. 1987-5

[10]
Immunochemical and biochemical characterization of tau proteins in normal and Alzheimer's disease brains with Alz 50 and Tau-1.

J Biol Chem. 1988-6-15

引用本文的文献

[1]
Twenty years of therapeutic development in tauopathy mouse models: a scoping review.

Alzheimers Dement. 2025-8

[2]
Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38α Mitogen-Activated Protein Kinase Inhibitors.

J Med Chem. 2025-8-28

[3]
Alzheimer's Disease Etiology Hypotheses and Therapeutic Strategies: A Perspective.

Int J Mol Sci. 2025-7-20

[4]
pS396/pS404 (PHF1) tau vaccine outperforms pS199/pS202 (AT8) in rTg4510 tauopathy model.

NPJ Vaccines. 2025-5-13

[5]
Tau Imaging: Use and Implementation in New Diagnostic and Therapeutic Paradigms for Alzheimer's Disease.

Geriatrics (Basel). 2025-2-14

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索