Yurumez Esra, Temelturk Rahime Duygu, Kaymak Banu, Karabıyıkoğlu Yağmur Özgür, Zengin Nisa Didem
Ankara University Faculty of Medicine, Department of Child and Adolescent Psychiatry, Ankara, Turkey; Ankara University, Autism Intervention and Research Center, Ankara, Turkey.
Ankara University Faculty of Medicine, Department of Child and Adolescent Psychiatry, Ankara, Turkey; Ankara University, Autism Intervention and Research Center, Ankara, Turkey; Ankara University Institute of Health Sciences, Department of Interdisciplinary Neuroscience, Ankara, Turkey.
Psychiatry Res. 2024 Dec;342:116250. doi: 10.1016/j.psychres.2024.116250. Epub 2024 Oct 28.
The current study aimed to evaluate subtle catatonia behaviors and functionality in adolescents with autism spectrum disorders (ASD). The sample consisted of 48 patients (11 female, 37 male) aged 12-18 (13.77 ± 2.01). DSM-5 catatonia criteria and Bush-Francis Catatonia Rating Scale (BCRS) was utilized to assess catatonia, while the impairment in functionality was appraised using the Global Assessment Scale. Parents fulfilled the Revised Child Anxiety and Depression Scale-Parent version (RCADS-PV) and Repetitive Behavior Scale-Revised (RBS-R). The presence of catatonia was detected in 18 out of 48 (37.5 %) participants according to BCRS, and in 16 cases (35.4 %) according to DSM-5 criteria. A significant association between two diagnostic tools was observed (p < 0.001). In the group with mild impairment in functionality, 2 cases had catatonia (12.5 %), while in the group with more impaired functionality, 16 cases (50 %) had catatonia (p = 0.011) according to BCRS. Major depressive disorder subscale scores of RCADS-PV and stereotypic movements (RBS-R) were correlated with the presence of catatonia (p < 0.05). The findings suggest a higher prevalence of catatonia in ASD, and a potential correlation between the presence of catatonia and functionality. More research is warranted to highlight the presence and course of catatonia beginning from the early years of ASD.
本研究旨在评估自闭症谱系障碍（ASD）青少年的细微紧张症行为及功能。样本包括48名患者（11名女性，37名男性），年龄在12 - 18岁之间（13.77±2.01）。采用《精神疾病诊断与统计手册》第五版（DSM - 5）紧张症标准和布什 - 弗朗西斯紧张症评定量表（BCRS）评估紧张症，同时使用整体评估量表评估功能损害情况。家长完成了修订版儿童焦虑抑郁量表家长版（RCADS - PV）和重复行为量表修订版（RBS - R）。根据BCRS，48名参与者中有18名（37.5%）检测出存在紧张症，根据DSM - 5标准则有16例（35.4%）。观察到两种诊断工具之间存在显著关联（p < 0.001）。根据BCRS，在功能轻度受损组中，有2例存在紧张症（12.5%），而在功能受损更严重的组中，有16例（50%）存在紧张症（p = 0.011）。RCADS - PV的重度抑郁障碍分量表得分和刻板动作（RBS - R）与紧张症的存在相关（p < 0.05）。研究结果表明ASD中紧张症的患病率更高，且紧张症的存在与功能之间可能存在关联。有必要进行更多研究以突出从ASD早期开始紧张症的存在情况及病程。
